Incidence rates for adenocarcinoma of the esophagus and gastric cardia have been rising rapidly. We examined nutrient intake as a risk factor for esophageal and gastric cancers in a population-based case-control study in Connecticut, New Jersey, and western Washington state. Interviews were completed for cases with histologically confirmed esophageal adenocarcinoma (n = 282), adenocarcinoma of ...

BACKGROUND Bariatric operations may alter esophageal motility; however, there is a paucity of studies of the esophageal motility with high resolution manometry. AIM To study patients after Roux-en-Y gastric bypass for morbid obesity with high resolution motility. METHODS Were included 18 asymptomatic patients (17 women, mean age 53 years) after undergoing to Roux-en-Y gastric bypass for mor...

background : although, family history of cancer is an important risk factor for upper gastrointestinal cancers development, but limited information is available on the upper gastrointestinal cancers associated with family history in iran. the purpose of this study was to define upper gastrointestinal cancers risk associated with family history of cancer. methods : this study was conducted as a ...

OBJECTIVE To summarize the endoscopic screening findings in high-risk population of esophageal and gastric carcinoma and analyze influential factors related to screening. METHODS In seven selected cities and counties with high incidences of esophageal carcinoma, people at age of 40-69 were set as the target population. Those with gastroscopy contradictions were excluded, and all who were volu...

The human microbiome Fusobacterium nucleatum, which primarily inhabits the oral cavity, causes periodontal disease and has also been implicated in the development of colorectal cancer. However, whether F. nucleatum is present in other gastroenterological cancer tissues remains to be elucidated. The present study evaluated whether quantitative polymerase chain reaction (qPCR) assays were able to...

Cancers of the esophagus and stomach present a major health burden worldwide. In the past 30 years we have witnessed some interesting shifts in terms of epidemiology of esophago gastric cancers. Regardless of a world region, the majority of patients diagnosed with esophageal or gastric cancers die from progression or recurrence of their disease. While there are many active cytotoxic agents for ...

BACKGROUND Several risk factors have been identified for esophageal adenocarcinoma, gastric cardia adenocarcinoma, esophageal squamous cell carcinoma, and noncardia gastric adenocarcinoma, but no study has comprehensively examined their contributions to the cancer burden in the general population. Herein, we estimate the population attributable risks (PARs) for various risk factors observed in ...

BACKGROUND Podocalyxin-like protein (PODXL) is a cell surface transmembrane glycoprotein, the expression of which has been associated with poor prognosis in a range of malignancies. The aim of this study was to investigate the impact of PODXL expression on survival in esophageal and gastric adenocarcinoma. METHODS The study cohort consists of a consecutive series of 174 patients with esophage...

.Yamaguchi Med J (Yamaguchi Igaku)53:103-107,200433) Motoyama S,Mori K,Maruyama K,Sato Y,Hayashi K,Usami S,Suzuki H,Ogawa J:S-1 chemotherapy for cancer of the gastric tube used for esophageal reconstruction following surgery for esophageal cancer(in Japanese with English abstract).Jpn J Cancer Chemother (Gan to Kagaku Ryoho)34:2287-2290,200734) Yamasawa K,Shimizu T,Shimosato A,Mihara F,...

Gastric varices represent an inhomogeneous entity morphologically, topographically and hemodynamically. Hence proper classification is mandatory not only to prognosticate but also to determine optimal therapeutic option. Although a number of classifications based on variceal location, morphology and color have been proposed, the one proposed by Sarin et al2 is most widely used and has been reco...