Several months have passed since news broke of a horrific compounding tragedy at the New England Compounding Center (NECC) in Framingham, Massachusetts. An outbreak of fungal meningitis in fall 2012 was traced to contaminated methylprednisolone acetate prepared by the NECC. According to the US Centers for Disease Control and Prevention (CDC), as of May 11, 2013, 55 deaths and a total case count...

Compounding, the process of combining several simplex words into a complex whole, is a productive process in a wide range of languages. In particular, concatenative compounding, in which the components are “glued” together, leads to problems, for instance, in computational tools that rely on a predefined lexicon. Here we present the AuCoPro project, which focuses on compounding in the closely r...

Nilavarai Curnam, a compound drug formulation in Siddha System of Medicine was analysed. The Microscopic methods of identifying their ingredients, Chemical analysis, Fluorescence, and Thin Layer Chromatographic studies of the drug have been reported here.

Effects of spatial compounding on image resolution and speckle noise are studied. Using computer simulation, it is shown that spatial compounding using averaged reconstruction can significantly improve lateral resolution while slightly deteriorate axial resolution. The amount of net resolution improvement depends mainly on the compound angle, but is insensitive to the number of component images...

PurposeTo expand on our 2015 study of the nicotine content accuracy e-liquids, including salts, and presence child-resistant packaging. We also describe compounding in shop (CIS).Design methodsWe analyzed samples from 35 shops. CIS processing was observed. Descriptive statistics summarized data, inference performed.ResultsActual significantly less than identified content, average, with a mean p...

The experience of art emerges from the interaction of various cognitive and affective processes. The unfolding of these processes in time and their relation with viewing behavior, however, is still poorly understood. Here we examined the effect of context on the relation between the experience of art and viewing time, the most basic indicator of viewing behavior. Two groups of participants view...

Investigating the methods commonly used to evaluate in vitro cytotoxicity of novel compounds, specifically non-covalent DNA binders, identifies that these methods may not be appropriate. The level of anticancer activity depends not only on the incubation time but also on the absolute amount (number of moles) of drug compound applied, rather than the concentration.

Optimal learning addresses the problem of efficiently collecting information with which to make decisions. These problems arise in both offline settings (making a series of measurements, after which a decision is made) and online settings (the process of making a decision results in observations that change the distribution of belief about future observations). Optimal learning is an issue prim...

The potential for contamination of compounded products and the resulting infections are a serious threat to patient safety. Immediate use products are used frequently in the perioperative department, and perioperative nurses should be familiar with the guidelines and practices that aim to reduce the contamination that can occur during the sterile compounding process. Four common themes lead to ...

The authors present a tokenizer and nite-state morphological analyzer [Beesley and Karttunen 2003] for Malagasy, based primarily on the discussion of Malagasy morphology in Keenan and Polinsky [1998] and Randriamasimanana [1986]. Words in Malagasy are built from roots by means of a variety of morphological operations such as compounding, afxation and reduplication. The authors analyze product...