The curriculum design, faculty characteristics, and experience of implementing masters' level international research ethics training programs supported by the Fogarty International Center was investigated. Multiple pedagogical approaches were employed to adapt to the learning needs of the trainees. While no generally agreed set of core competencies exists for advanced research ethics training, ...

BACKGROUND Approval of the research proposal by an ethical review committee from both sponsoring and host countries is a generally agreed requirement in externally sponsored research.However, capacity for ethics review is not universal. Aim of this study was to identify opinions and views of the members serving in ethical review and ethics committees in Sri Lanka on informed consent, essential ...

Severity (harm, invasiveness) scales focus the attention of both regulators and researchers on highly invasive experiments and thus help to promote the 3Rs, especially the refinement. A severity scale is critical to the quality of ethical review processes (ERPs) in limiting arbitrariness and situational opportunism of assessments, defining the acceptability ranges for some animal uses, especial...

INTRODUCTION There are an increasing number of people living with and beyond cancer, whose experience is further complicated by additional long-term health conditions in the context of an ageing population. The supportive care needs of this growing patient group should be recognised and addressed. There is a need to explore the experience of living with cancer and comorbid illness in order to d...

The Good Clinical Practices (GCP) codes of the WHO and the International Conference of Harmonization set international standards for clinical research. But critics argue that they were written without consideration for the challenges faced in low and middle income countries (LMICs). Based on our field experience in LMICs, we developed a non-exhaustive set of recommendations for the improvement ...

L ibrary and Archives Canada (LAC) contains a number of resources relevant to Indigenous heritage, among them the School Files Series which contains government records created from 1879 to 1953 about residential and day schools operating in Canada and available on microfilm. In recent years, many of these microfilm images have been digitized and made available on the LAC and other websites. The...

PURPOSE Globally, prostate cancer treatment and outcomes for men vary according to where they live, their race and the care they receive. The TrueNTH Global Registry project was established as an international registry monitoring care provided to men with localised prostate cancer (CaP). PARTICIPANTS Sites with existing CaP databases in Movember fundraising countries were invited to participa...

BACKGROUND Community consultation is increasingly recommended, and in some cases, required by ethical review boards for research that involves higher levels of ethical risk such as international research and research with vulnerable populations. In designing a randomised control trial of a mental health intervention using a wait list control, we consulted the community where the research would ...

BACKGROUND Institutional review boards (IRBs) distinguish health care quality improvement (QI) and health care quality improvement research (QIR) based primarily on the rigor of the methods used and the purported generalizability of the knowledge gained. Neither of these criteria holds up upon scrutiny. Rather, this apparently false dichotomy may foster under-protection of participants in QI pr...