Optically active tertiary aminonaphthol ligands were obtained by a new, convenient procedure and were found to catalyze the enantioselective alkenyl and phenyl transfer to aldehydes in high yields and excellent enantiomeric excesses (ee’s). The catalytic asymmetric introduction of alkynyl functionality to α-amino acid derivatives was realized by the direct addition of terminal alkynes to α-imin...

background and aim: neonatal jaundice is one of the common causes of early sensori­neural hearing loss and an important cause of deafness in children. auditory responses are the most sensitive parts of the nervous system to the toxic effect of bilirubin. this study was aimed to examine the effect of neonatal hyperbili­rubinemia and its treatment on auditory brain­stem responses (abr). methods: ...

this condition is due to deficiency in electron transport flavoprotein or electron transport fluvoprotein dehydrogenase.the clinical presentation is characteristic of fatty acid oxidation disorders. this disorder is poor prognostic and death in infancy is common.the central nervous system involving causes neurodevelopmental delay, hypotonia, and head lag. different type of seizures such as infa...

Acute cellular rejection (ACR) and hepatitis C virus (HCV) recurrence (HCVrec) are common complications after liver transplantation (LT) in HCV patients, who share common clinical and histological features, making a differential diagnosis difficult. Fifty-three liver allograft samples from unique HCV LT recipients were studied using microarrays, including a training set (n = 32) and a validatio...

how to cite this article: dara n, sayyari aa, imanzadeh f. hepatic encephalopathy: early diagnosis in pediatric patients with cirrhosis. iran j child neurol. 2014 winter; 8(1):1-11. objective as acute liver failure (alf) and chronic liver disease (cirrhosis) continue to increase in prevalence, we will see more cases of hepatic encephalopathy. primary care physician are often the first to suspec...

how to cite this article: salehi omran mr, nooreddini h, baghdadi f. acute necrotizing encephalopathy of childhood; a case report. iran j child neurol. 2013 spring;7(2):51-54.   abstract acute necrotizing encephalopathy of childhood (anec) is an atypical disease followed by respiratory or gastrointestinal infection, high fever, which is accompanied with rapid alteration of consciousness and sei...

how to cite this article: sharifian m. hypertensive encephalopathy. iran j child neurol 2012; 6(3):1-7. hypertension is called the silent killer and vital organs such as the brain, eyes,kidneys and the heart are the targets. seizure, central nervous system (cns)hemorrhage, and cerebrovascular accident (cva), blindness and heart attacksare the end points.the prevalence of hypertension in childre...