An increasing incidence of invasive fungal infections is observed in most immunocompromised patients, and especially leukaemia patients. In order to decrease the mortality due to these infections, the clinicians need to optimise their treatment choices for the most common fungal infections observed in this population: invasive aspergillosis and candidiasis. These recommendations have been devel...

The Agency for Healthcare Research and Quality (AHRQ), through its Evidencebased Practice Centers (EPCs), sponsors the development of evidence reports and technology assessments to assist publicand private-sector organizations in their efforts to improve the quality of health care in the United States. The reports and assessments provide organizations with comprehensive, science-based informati...

It is a great honour to be asked to comment on Dr Tonelli’s paper ‘Integrating evidence into clinical practice, an alternative to evidence-based approaches’. Dr Tonelli has consistently been one of the more thoughtful commentators on the evidencebased medicine (EBM) debate and, in fact, published one of the first critiques of EBM from a philosophical point of view (Tonelli 1998). In this paper,...

We have entered a new therapy-world called the world of evidence-based practice. That this world is new is, in its own way, rather odd. On one level of thinking, one would hope that we have engaged in evidence-based practice for a long time already, if not forever. Surely, none of us engages in therapy strategies and techniques that have no evidence for being effective, do we? Well, yes and no....

473 There is a need for occupational therapy to conceive of evidence-based practice in a way that reflects the contextualized nature of occupational engagement. In occupational therapy, we should resist following the lead of experts in evidence-based medicine, such as Sackett and his colleagues (Rosenberg & Donald, 1995; Sackett, Rosenberg, Gray, Haynes, & Richardson, 1996; Sackett, Straus, Ric...

The Pediatric Eye Disease Investigator Group (PEDIG) was established in 1997 to create a network of investigators to undertake clinical research into pediatric eye problems. The group was conceived by Roy W. Beck, M.D., Ph.D., in response to the call for large, simple trials from the National Institutes of Health.1 The research group was created to develop clinical trials exploring common probl...

Evidence-Based Practice (EBP) represents a decision-making process centered on justifications of relevant information. Context is a kind of knowledge that supports the ability to define what is or is not relevant in a given situation. The decision-making context can have an impact on evidencebased decision-making, but the integration of evidence and context is still an open issue. Ontology is r...

Peer support is unique in the mental health field because peer specialists provide a role model of recovery to both staff and people in recovery. Peer support as an evidencebased practice is reviewed. A personal recovery story and the experience of working as a certified peer specialist are shared to show the power peer supporters have in transforming the mental health system. Research supporti...

Abstract: The purpose of this study was to provide a synthesis of research studies published in the last ten years on interventions to increase social skills for children and adolescents with ASD, examine the outcomes of these studies and evaluate whether a given intervention meets the criteria for evidence-based practice. Thirty-eight studies were included in this review, of which 36 were sing...

Evidenced-based medicine (EBM) is a philosophic approach to clinical problems introduced in the 1980s by a group of clinicians at McMaster University in Canada with an interest in clinical epidemiology. The concepts associated with EBM have been widely disseminated. While many feel EBM represents a paradigm shift, others have debated the usefulness of this approach. In this chapter we will prov...