Supernates derived from incubated lymph node cells of Lewis rats sensitized to guinea pig spinal cord-Freund's adjuvant transfer experimental allergic encephalomyelitis (EAE) to syngeneic recipients. EAE supernatant transfer activity (EAE-STA) is not demonstrable in supernates derived from LNC of control donors not sensitized to nervous tissue. After addition of brain antigen to active supernat...

A Study of Passive Sensitization of Guinea Pigs with Antigen-Antibody Complexes. LEON T. ROSENBER¢~ AND DORA K. TACHIBANA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 Specificity of Encephalitogen-Induced Inhibition of Experimental "Allergic" Encephalomyelitis in the Guinea Pig. CHENG-MEI SHAW, ELLSWORTH C. ALvom), JR., WILLSON J. FAHLBERG AND MARIAN W. KIES . . . . . . . ...

Cop 1 is a synthetic basic random copolymer of L-alanine, L-glutamic acid, L-lysine, and L-tyrosine in a residue molar ratio of 6.0:1.9:4.7:1.0 and with a molecular weight of 21,000 which proved to be effective in specific suppression of experimental allergic encephalomyelitis and has been proposed as a candidate drug against multiple sclerosis. In the present study we further investigated the ...