BACKGROUND Previous studies have discussed attitudes of vitiligo patients toward their disease. However, no studies have addressed this issue from the public's point of view. OBJECTIVE To explore the perceptions, attitudes, and misconceptions of the public toward vitiligo. METHODS A self-administered questionnaire was distributed to attendees of primary health care centers in Riyadh, Saudi ...

Background. There are limited epidemiological studies evaluating the effect of age at onset on disease features in vitiligo. Objectives. To identify factors associated with adult onset vitiligo in comparison with childhood onset vitiligo. Patients and Methods. We retrospectively collected medical records of 191 patients. Such records included clinical examination, personal and familial medical ...

BACKGROUND/AIM Reduced vitamin D is considered as one of the environmental factors that can increase the prevalence of certain autoimmune diseases. This study aimed to assess vitamin D metabolism in patients with vitiligo. MATERIALS AND METHODS A prospective case-control study was conducted on 44 consecutive patients with vitiligo vulgaris and 43 healthy controls. Their plasma 25-hydroxyvitam...

INTRODUCTION: Vitiligo is an acquired autoimmune skin disease clinically manifested by foci of depigmentation due to the death epidermal melanocytes. Although vitiligo most often runs in isolation, being limited a pathological process skin, this can lead development number comorbid disorders. Alopecia areata also disorder appendages, one common disorders vitiligo, manifesting along with main di...

Sir, Many years after publication of the last comprehensive treatise on vitiligo (1), two recent books (2, 3) provide a thorough review of the literature on this common autoimmune disorder. Interestingly, while vitiligo may be associated with one or several of many systemic abnormalities (2), to our knowledge there have been no reports of its association with Sjögren’s syndrome, another autoimm...

BACKGROUND Vitiligo is an acquired depigmenting disorder due to destruction of melanocytes. Although many theories have been suggested for its pathogenesis, the role of autoimmunity is the most popular one. The association of vitiligo with autoimmune thyroid diseases and the increased prevalence of autoantibodies including thyroid autoantibodies in vitiligo favor this role. Our objective was to...

Vitiligo is an autoimmune disease with a strong genetic component, characterized by areas of depigmented skin resulting from loss of epidermal melanocytes. Genetic factors are known to play key roles in vitiligo through discoveries in association studies and family studies. Previously, vitiligo susceptibility genes were mainly revealed through linkage analysis and candidate gene studies. Recent...

Background: Vitiligo is a dermatological disorder of unknown etiology with a common incidence in southern Iran. Presence of autoantibodies to melanocyte antigens suggested an autoimmune basis of the disease. Objective: In this study, the presence of rheumatoid factor (RF) in sera and skin biopsies of vitiligo patients was investigated. Methods: The presence of RF in sera of 35 vitiligo and 32 n...

background: vitiligo is a dermatological disorder of unknown etiology with a common incidence in southern iran. presence of autoantibodies to melanocyte antigens suggested an autoimmune basis of the disease. objective: in this study, the presence of rheumatoid factor (rf) in sera and skin biopsies of vitiligo patients was investigated. methods: the presence of rf in sera of 35 vitiligo and 32 n...

Obviously, vitiligo is a multifactorial disease, and at this stage, we all accept that the autoimmune theory, the adhesion defect theory and the biochemical theory based on oxidative stress are the mainstays of our current knowledge about the aetiology of the disease. The presence of an imbalance in the anti-oxidant system in vitiligo melanocytes was assessed early, providing support for a free...