Although endosomal compartments have been suggested to play a role in unconventional protein secretion, there is scarce experimental evidence for such involvement. Here we report that recycling endosomes are essential for externalization of cytoplasmic secretory protein tissue transglutaminase (tTG). The de novo synthesized cytoplasmic tTG does not follow the classical ER/Golgi-dependent secret...

Collaborative learning is widely used in classroom activities. The screens of handheld devices, designed for individual-user mobile application, which may constrain the interactions among group learners. The small size of screen may lead to fragmented and tête-à-tête communication pattern, and frequently obstacle the externalization of student learning process. This study proposes a shared disp...

BACKGROUND In adults with antisocial personality disorder, marked alterations in the recognition of facial affect were described. Less consistent data are available on the emotion recognition in adolescents with externalization problems. The aim of the present study was to assess the relation between the recognition of emotions and conduct symptoms in adolescent boys with externalization proble...

BACKGROUND Germ cell elimination and sperm DNA fragmentation in men with primary testiculopathies involve apoptosis-related processes whose mechanisms are poorly understood. This study examines the participation of typical (caspase-dependent) and atypical (caspase-independent) pathways in these processes. METHODS Caspase activity and DNA fragmentation were evaluated in Sertoli and germ cells ...

This study intends to identify the establishment of Islamic social construction in Shi’a community Pekalongan City. Qualitative research applied this gathered from case studies using a phenomenological approach. Data came in-depth observation, interviews, and documentation. The theory formulated by Peter L. Berger Thomas Luckmann became basic analysis. results showed that Islam City was formed ...

We report on on-going work investigating the feasibility of using tissue conduction to evince auditory spatial perception. Early results indicate that it is possible to coherently control externalization, range, directionality (including elevation), movement and some sense of spaciousness without presenting acoustic signals to the outer ear. Signal control techniques so far have utilised discre...

BACKGROUND Our previous study had shown that P. amaryllifolius was able to selectively inhibit cell proliferation of hormone independent breast cancer cell line MDA-MB-231. To understand the mode of killing and mechanism of action for P. amaryllifolius, the ethanol extract was evaluated for their alteration of cell cycle progression, PS externalization, DNA fragmentation and expression of anti/...

Introduction According to the classic view of labour markets, workers move freely from job to job and firm to firm (Bakke, 1954). From the worker’s perspective, this movement is governed by pressures to maximize the fit between worker skills and job requirements, with the objective of maximizing earnings. Historically, however, hierarchical (internal) control of labour supplanted the open labou...

Due to the vagueness of the concept of knowledge, the software market for knowledge management (KM) seems to be quite confusing. Technology vendors are developing different implementations of the KM concepts in their software products. Because of the variety and quantity of KM tools available on the market, a typology may be a valuable aid to organizations that are searching and evaluating KM s...