PURPOSE Wedelia chinensis is a common ingredient of anti-inflammatory herbal medicines in Taiwan and southern China. Inflammation is involved in promoting tumor growth, invasion, and metastasis. This study aims to test the biological effects in vivo of W. chinensis extract on prostate cancer. EXPERIMENTAL DESIGN The in vivo efficacy and mechanisms of action of oral administration of a standar...

This work was aimed to study the stability, and activity of topical products formulated with red leaves extract Vitis Vinifera encapsulated in liposomes, produced, Tuscany (Italy). Recent studies have suggested a possible moisturizing elasticizing Vinifera. For such characteristics appears an appropriate ingredient be used preparations for treatment skin hydration. The liposomes then incorporat...

Endothelin-1 (ET-1) has been reported to be expressed in human epidermis at both the gene and protein levels. ET-1 plays a pivotal role in ultraviolet B (UVB)-induced pigmentation due to its accentuated secretion after UVB irradiation and its function as a mitogen and as a melanogen for human melanocytes. We have recently found that endothelin-converting enzyme (ECE)-1alpha plays a constitutive...

BACKGROUND Vector control is facing a threat due to the emergence of resistance to synthetic insecticides. Insecticides of botanical origin may serve as suitable alternative biocontrol techniques in the future. Although several plants have been reported for mosquitocidal activity, only a few botanicals have moved from the laboratory to field use, because they are poorly characterized, in most c...

The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...

Objective: Rosa beggeriana Schrenk has been consumed in Iranian traditional medicine. In contrary to its close species (e.g. R. canina), there is no data on its medicinal properties. Therefore, we explored possible cytotoxic effects of R. beggeriana against two cancer cell lines. Materials and Methods: The cytotoxic and anti-pro...

The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...