Pellet additive manufacturing (PAM) is in terms of printing process very similar to the widely used fused deposition modelling (FDM) systems. The main difference use pellets instead filament. In this study, a pellet, single screw extruder developed. A design with variable pitch and depth modelled analytically predict melting behavior acrylonitrile butadiene styrene (ABS) during steady state ext...

The main aim of the present study was to evaluate the potential of orally disintegrating pellets (ODPs) as an approach for taste masking of bitter drugs, namely, Ambroxol hydrochloride (A-HCl) and Cetirizine dihydrochloride (C-DHCl). Pellets were prepared by extrusion/spheronization with Eudragit EPO, kyron T-134, Kyron T-314, mannitol, sorbitol, MCC (Avicel PH-101), sucralose, chocolate flavor...

Extrusion cooking is a continuous mixing, cooking, and forming processing method. The main objective of the study was to determine effect inclusion chemical silage residues from benefit trout (Oncorhynchus mykiss) in extrusion process food diet for fish. evaluation hydrolyzed protein flour (HPF) carried out simple screw extruder, using 2k factorial design, with four factors: temperature profile...

*To whom all correspondence should be addressed. uring the past few decades, various types of oral controlled-release (CR) formulations have been developed to improve the clinical efficacy of drugs having short half lives as well as to increase patient compliance (1, 2). These formulations are designed to deliver drugs at a predetermined rate over a wide range of conditions and durations of the...

BACKGROUND Amoxicillin is a commonly used antibiotic which has a short half-life in human. The frequent administration of amoxicillin is often required to keep the plasma drug level in an effective range. The short dosing interval of amoxicillin could also cause some side effects and drug resistance, and impair its therapeutic efficacy and patients' compliance. Therefore, a three-pulse release ...