نتایج جستجو برای: familial aggregation

تعداد نتایج: 119466  

Journal: :Journal of Investigative Dermatology 2000

Journal: :Scandinavian Journal of Work, Environment & Health 1984

Journal: :Environmental Health Perspectives 1990

Journal: :Collegium antropologicum 2009
Badaruddoza Rashveen Sawhney

This study aimed to examine the familial aggregation of blood pressure with respect to anthropometric variables in an upper-middle class business community in Punjab, a northern state of India. The results were evaluated in a sample of 75 families, constituting 305 individual from three generations such as offspring, parental and grandparental. The data were analyzed through familial correlatio...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2004
J Lorenzo Bermejo F L Büchner K Hemminki

BACKGROUND Endometrial cancer is the second most common lesion within hereditary non-polyposis colorectal cancer (HNPCC) syndrome. The importance of the non-HNPCC genetic predisposition to endometrial cancer is unclear, and the familial aggregation of endometrial cancer after exclusion of HNPCC families may offer valuable clues about the involvement of non-HNPCC-related genes. PATIENTS AND ME...

Journal: :Archives of general psychiatry 1998
L R Lilenfeld W H Kaye C G Greeno K R Merikangas K Plotnicov C Pollice R Rao M Strober C M Bulik L Nagy

BACKGROUND We used contemporary family-epidemiological methods to examine patterns of comorbidity and familial aggregation of psychiatric disorders for anorexia and bulimia nervosa. METHODS Direct interviews and blind best-estimate diagnostic procedures were used with diagnostically "pure" groups of probands with eating disorders and a matched control group. Lifetime prevalence rates of eatin...

Journal: :Clinical and experimental rheumatology 2009
E Liozon B Ouattara K Rhaiem K Ly H Bezanahary V Loustaud P Letellier M Drouet E Vidal

OBJECTIVE To review personal and published observations of giant cell (temporal) arteritis (GCA) or polymyal-gia rheumatica (PMR) with familial or conjugal aggregation and emphasise on epidemiological, clinical and genetic features of such cases. METHODS We pooled data obtained from all cases of GCA or PMR with familial aggregation recruited in the department since 1976 and those from reports...

Journal: :Cancer discovery 2016
Nicholas J Roberts Alexis L Norris Gloria M Petersen Melissa L Bondy Randall Brand Steven Gallinger Robert C Kurtz Sara H Olson Anil K Rustgi Ann G Schwartz Elena Stoffel Sapna Syngal George Zogopoulos Syed Z Ali Jennifer Axilbund Kari G Chaffee Yun-Ching Chen Michele L Cote Erica J Childs Christopher Douville Fernando S Goes Joseph M Herman Christine Iacobuzio-Donahue Melissa Kramer Alvin Makohon-Moore Richard W McCombie K Wyatt McMahon Noushin Niknafs Jennifer Parla Mehdi Pirooznia James B Potash Andrew D Rhim Alyssa L Smith Yuxuan Wang Christopher L Wolfgang Laura D Wood Peter P Zandi Michael Goggins Rachel Karchin James R Eshleman Nickolas Papadopoulos Kenneth W Kinzler Bert Vogelstein Ralph H Hruban Alison P Klein

UNLABELLED Pancreatic cancer is projected to become the second leading cause of cancer-related death in the United States by 2020. A familial aggregation of pancreatic cancer has been established, but the cause of this aggregation in most families is unknown. To determine the genetic basis of susceptibility in these families, we sequenced the germline genomes of 638 patients with familial pancr...

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