BACKGROUND Late-life depression (LLD) in the elderly was reported to present with emotion dysregulation accompanied by high perceived loneliness. Previous research has suggested that LLD is a disorder of connectivity and is associated with aberrant network properties. On the other hand, perceived loneliness is found to adversely affect the brain, but little is known about its neurobiological ba...

Both social isolation and loneliness are associated with increased mortality, but it is uncertain whether their effects are independent or whether loneliness represents the emotional pathway through which social isolation impairs health. We therefore assessed the extent to which the association between social isolation and mortality is mediated by loneliness. We assessed social isolation in ter...

BACKGROUND Depression and loneliness are prevalent and highly correlated phenomena among the elderly and influence both physical and mental health. Brain functional connectivity changes associated with depressive symptoms and loneliness are not fully understood. METHODS A cross-sectional functional MRI study was conducted among 85 non-demented male elders. Geriatric depression scale-short for...

OBJECTIVES To assess the relationship between various social isolation indicators and loneliness, and to examine the differential associations that social isolation indicators, loneliness have with depressive symptoms. METHODS Baseline data for 1,919 adults (aged 21 years and above) from a representative health survey in the Central region of Singapore was used for this study. The association...

BACKGROUND While loneliness has been regarded as a risk to mental and physical health, there is a lack of current community data covering a broad age range. This study used a large and representative German adult sample to investigate loneliness. METHODS Baseline data of the Gutenberg Health Study (GHS) collected between April 2007 and April 2012 (N = 15,010; 35-74 years), were analyzed. Recr...

Study aims were to: (a) describe normative levels and person-oriented developmental trends in loneliness across adolescence, and (2) examine the association between loneliness and depressive symptoms during this same epoch. Participants included 478 youth (239 males and females; 80% Caucasian, 16% African American, and 4% other). Measures of loneliness and multiple indicators of depressive symp...

We present evidence from a 5-year longitudinal study for the prospective associations between loneliness and depressive symptoms in a population-based, ethnically diverse sample of 229 men and women who were 50-68 years old at study onset. Cross-lagged panel models were used in which the criterion variables were loneliness and depressive symptoms, considered simultaneously. We used variations o...

Eight studies found a robust negative relationship between the experience of power and the experience of loneliness. Dispositional power and loneliness were negatively correlated (Study 1). Experimental inductions established a causal connection: we manipulated high versus low power through autobiographical essays, assignment to highversus low-power positions, or control over resources, and fou...

This article provides a commentary on a set of five other articles reporting European and Canadian studies of loneliness among seniors. It places those works involving Canadian, Dutch, Finnish, and Welsh samples in the larger context of research on loneliness; offers reflections on the methods and findings reported in the articles; and addresses the question, Is loneliness universal? Points of ...

BACKGROUND Research on the association between adult attention-deficit/hyperactivity disorder (ADHD) and loneliness is scarce even though factors which have been previously linked to loneliness, such as divorce and poorer mental health may be more prevalent among adults with ADHD. This study investigated the relation between ADHD symptoms/symptom severity and loneliness in the general adult pop...