نتایج جستجو برای: familial resemblance

تعداد نتایج: 61875  

2017
Leonie H. Bogl Karri Silventoinen Antje Hebestreit Timm Intemann Garrath Williams Nathalie Michels Dénes Molnár Angie S. Page Valeria Pala Stalo Papoutsou Iris Pigeot Lucia A. Reisch Paola Russo Toomas Veidebaum Luis A. Moreno Lauren Lissner Jaakko Kaprio

Information on familial resemblance is important for the design of effective family-based interventions. We aimed to quantify familial correlations and estimate the proportion of variation attributable to genetic and shared environmental effects (i.e., familiality) for dietary intake variables and determine whether they vary by generation, sex, dietary quality, or by the age of the children. Th...

Journal: :American journal of human genetics 1978
J Rice C R Cloninger T Reich

A general linear model of familial resemblance is described which allows for cultural transmission from parent to offspring, polygenic inheritance, phenotypic assortative mating, common environment, maternal and paternal effects, and threshold effects. Three special cases are described in detail which are particularly useful when data are only available about a few classes of relatives reared i...

Journal: :The American journal of psychiatry 1994
K S Kendler E E Walters K R Truett A C Heath M C Neale N G Martin L J Eaves

OBJECTIVE Self-reported symptoms of depression are commonly used in mental health research to assess current psychiatric state, yet wide variation in these symptoms among individuals has been found in both clinical and epidemiologic populations. The authors sought to understand, from a genetic-epidemiologic perspective, the sources of individual differences in depressive symptoms. METHODS Sel...

Journal: :Archives of general psychiatry 2004
Brian M Hicks Robert F Krueger William G Iacono Matt McGue Christopher J Patrick

BACKGROUND Antisocial behavior and substance dependence disorders exact a heavy financial and human cost on society. A better understanding of the mechanisms of familial transmission for these "externalizing" disorders is necessary to better understand their etiology and to help develop intervention strategies. OBJECTIVES To determine the extent to which the family transmission of externalizi...

Journal: :The Journal of clinical endocrinology and metabolism 2006
J M Vink S Sadrzadeh C B Lambalk D I Boomsma

BACKGROUND Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of reproductive age. There is evidence for a genetic component in PCOS based on familial clustering of cases. OBJECTIVE In the present study, the heritability of PCOS was estimated. DESIGN/PARTICIPANTS Data from 1332 monozygotic twins (genetically identical) and 1873 dizygotic twins/singlet...

Journal: :Hypertension 1999
C N Rotimi R S Cooper G Cao O Ogunbiyi M Ladipo E Owoaje R Ward

Elevated blood pressure (BP) is more common in relatives of hypertensives than in relatives of normotensives, indicating familial resemblance of the BP phenotypes. Most published studies have been conducted in westernized societies. To assess the ability to generalize these estimates, we examined familial patterns of BP in a population-based sample of 510 nuclear families, including 1552 indivi...

Journal: :Psychological medicine 2002
E O'Mahony A Corvin R O'Connell C Comerford B Larsen R Jones F McCandless G Kirov A G Cardno N Craddock M Gill

BACKGROUND As part of a collaborative linkage study, the authors obtained clinical and demographic data on 160 families in which more than one sibling was affected with a bipolar illness. The aim of the study was to identify clinical characteristics that had a high degree of familiality. METHOD Data on age at onset, gender, frequency of illness-episodes and proportion of manic to depressive e...

Journal: :acta medica iranica 0
p. fard-esfahani p. mohammadi-torbati s. khatami s. zeinali m. taghikhani m. allahyari

familial defective apolipoprotein (apo) b 100 (fdb) causes early-onset coronary heart diseases (chd). it is produced by r3500q mutation of the apob gene resulting in decreased binding of ldl to ldl receptor. we screened the apo b gene for r3500q mutation in 130 hypercholesterolemic patients, among whom 30 patients met criteria of familial hypercholesterolemia (fh). the prevalence of r3500q alle...

Journal: :Functional Ecology 2019

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