Sister chromatid cohesion refers to the process by which sister chromatids are tethered together until the metaphase-to-anaphase transition. The evolutionarily conserved cohesin complex mediates sister chromatid cohesion. Cohesin not only ensures proper chromosome segregation, but also promotes high-fidelity DNA repair and transcriptional regulation. Two subunits of cohesin (Smc1p, Smc3p) are m...

In mitosis and meiosis, cohesion is maintained at the centromere until sister-chromatid separation. Drosophila MEI-S332 is essential for centromeric cohesion in meiosis and contributes to, though is not absolutely required for, cohesion in mitosis. It localizes specifically to centromeres in prometaphase and delocalizes at the metaphase-anaphase transition. In mei-S332 mutants, centromeric sist...

Cohesion is considered as one of the most important software quality attributes. Cohesion refers to the degree of relatedness between members of a software component. Cohesion is one of the few internal software attributes that has been both theoretically and empirically shown to have large impact on external software quality characteristics like maintainability, modularity, reusability, testab...

BACKGROUND Sister-chromatid cohesion depends on the cohesin complex whose association with chromatin is mediated by Scc2 and Scc4 in budding yeast. Both cohesin and Scc2 have been conserved from yeast to humans, but no Scc4 orthologs have been identified. Mutation of Scc2 orthologs causes defects in cohesion, transcription, and development, resulting in Cornelia de Lange syndrome in humans. R...

The purpose of the present paper is to peruse the sociological effects of media on youth domestic values. The statistical population consists of the cities of Mazandaran in 2016 which have access to the sociological effects of media on youth domestic values with utilizing a simple random sampling technique. The statistical population consisted of 110, 321 youth (men and women) at Mazandaran. A ...

The social cohesion of a group, as measured by patterns of network ties, increases with the level of redundancy of interconnections of its members. We will see that the minimal number k of independent paths that connect every pair of actors in a group, the higher the cohesion. The cohesiveness of a group is also measured by the extent to which it is not disconnected by removal of 1, 2, 3,..., n...

OBJECTIVE This study's aim was to investigate the association between family structure and different health-related outcomes in adolescence (self-rated health, emotional and behavioural problems, health-related quality of life, regular smoking, and heavy episodic drinking). Furthermore, we analysed the extent to which socio-economic status, family cohesion and the pre-transition health status e...

The aim of this study was to investigate the relationship between inadequate nutrient intake, oral health and family cohesion. This was a crosssectional study with a sample of 887 non-institutionalized elderly people from Vitória, Espírito Santo State, Brazil. Oral examination was performed by trained and calibrated examiners and three measurements were considered: number of posterior occluding...

OBJECTIVE To investigate effects of pediatric head trauma on parent mental health, parent-child relationship and family functioning 2 weeks after discharge. METHODS Ninety-seven mothers and 37 fathers of 106 preschool children hospitalized with head injury completed Mental Health Inventory (MHI), Parenting Stress Index, Family Adaptability and Cohesion Evaluation Scales II (FACES II) and Mult...