RESEARCH DESIGN AND METHODSdOne-thousand two-hundred sixty-four individuals without known diabetes in the Diabetes Community Lifestyle Improvement Program in Chennai, India, had a 75-g oral glucose tolerance test, with glucose and insulinmeasured at 0, 30, and 120min. Type 2 diabetes, isolated impaired fasting glucose (iIFG), isolated impaired glucose tolerance (iIGT), combined impaired fasting...

OBJECTIVE To identify the effect of some herbal products on insulin resistance. Regarding the scientific evidences existing about ginger, this research was therefore carried out to identify the effect of ginger supplementation on insulin resistance and glycemic indices in diabetes mellitus. METHODS This is a randomized, double-blind, placebo-controlled trial in which 88 participants affected ...

AimsTo correlate the waist-to-height ratio (WHt-R) with Matsuda index of Oral Glucose Tolerance Test (OGTT) and other surrogate indices fasting insulin resistance/sensitivity to derive a cut-off value for WHt-R in lean, normoglycaemic males from Southern India.MethodsA cohort 105 (mean BMI: 19.2 ± 2.6 kg/m2) underwent OGTT. Surrogate resistance viz, Homeostatic model assessment Insulin Resistan...

AIM To investigate the impact of hypothyroidism and thyroxine therapy on insulin sensitivity in patients with overt hypothyroidism. METHODS The study included twenty seven overtly hypothyroid and fifteen healthy euthyroid South Western Asian females. Both groups had matching age and body mass index. Physiological and pathological conditions as well as medications that may alter thyroid functi...

BACKGROUND We developed a simple and new insulin resistance index derived from a glucose clamp and a meal tolerance test (MTT) in Japanese patients with type 2 diabetes mellitus. METHODS Fifteen patients [mean age: 53 years, fasting plasma glucose (FPG) 7.7 mmol/L, HbA1c 7.1% (54 mmol/mol), body mass index 26.8 kg/m(2)] underwent a MTT and a glucose clamp. Participants were given a test meal ...

OBJECTIVE To find out if pregnancy in black Zimbabwean women is a diabetogenic state using basal blood levels of cortisol, insulin, C-peptide and glucose. METHODS 111 women (28 non-pregnant, 29 first trimester, 26 second trimester and 28 third trimester) aged between 18 and 35 years were recruited for the study. Fasting plasma cortisol, insulin, C-peptide and glucose were determined by standa...

Background: Polycystic ovarian syndrome is one of the most commen hyper androgenic disorders affecting women, its prevalence being estimated at 5% – 10%. Our goal was to survey abnormal glucose tolerance, insulin resistance and incidence of diabetes type 2 in patients with polycystic ovary syndrome. Materials and methods: This investigation is a descriptive – analytic study which is done to su...

background and objectives: the prevalence of diabetes mellitus (insulin resistance) in individuals with down's syndrome is more than healthy people, which is possibly because of the high prevalence of obesity among them. adiponectin is one of adipose tissue-secreted adipocytokines, which plays a role in pathogenesis of obesity and insulin resistance. this study was carried out with the aim of d...

Background and objectives: Although the efficacy of selected training and antioxidant herbs in the treatment of diabetes mellitus has been determined, the interactive effect of selected training and aqueous extract of barberry on insulin resistance and risk factors of type2 diabetes mellitus is not well understood. The aim of the present study was to investigate the effect of aqueous extract of...

OBJECTIVE To investigate the clinical efficacy of gastric bypass surgery in non-obese patients with type 2 diabetes. METHODS Clinical data of 58 non-obese patients with type 2 diabetes (body mass index range from 22.1-25.8 kg/m(2)) were collected one year after gastric bypass surgery. Collected parameters included fasting plasma glucose, 2-hour postprandial blood glucose, glycosylated hemoglo...