UNLABELLED The Neurological Fatigue Index for Multiple Sclerosis (NFI-MS) is a new fatigue assessment instrument. The aim of this study was to cross-culturally adapt and assess the psychometric properties of the Brazilian version of the NFI-MS (NFI-MS/BR). METHOD Two hundred and forty subjects with MS were recruited for this study. The adaptation of the NFI-MS was performed by translation and...

BACKGROUND The clinical impact of neutralizing antibodies against interferon-beta (NAb) is controversial. Their presence can lead to a decrease in interferon-beta (IFNβ) efficacy. Fatigue reported in patients with multiple sclerosis (MS) may be associated with an unfavorable clinical course. We conducted a prospective multicentre study to assess the association between response to IFNβ, NAb and...

I read with great interest the article by Strand et al. The aim of the study was to assess the effects of belimumab treatment plus standard systemic lupus erythematosus (SLE) therapy on health-related quality of life in patients with active, autoantibody-positive SLE. Of particular interest are the results about the impact of belimumab on fatigue scores. Fatigue is a common complaint of patient...

driver fatigue is one of the main causes of road accidents. this study aimed to estimate bus driver fatigue through performance measures in a virtual driving environment. the study was conducted on thirty professional male bus drivers participated in a two-hour drive session. the driver subjective fatigue was assessed by fatigue visual analogue scale (f-vas) on 10 min intervals. at the same tim...

background: fatigue, depression, and physical impairment are common  among  multiple  sclerosis (ms) patients. the aim  of  this  study was to  determine  the   relationship between depression,  physical impairment,  and  fatigue  in an iranian ms cohort. methods: fifty consecutive  relapsing-remitting ms patients and  50 age- and  sex-matched healthy  controls (hcs) were recruited  from sina r...

OBJECTIVES To investigate the effect of group cognitive behavioural therapy (CBT) for fatigue self-management, compared with groups receiving fatigue information alone, on fatigue impact among people with rheumatoid arthritis (RA). METHODS Two-arm, parallel randomised controlled trial in adults with RA, fatigue ≥ 6/10 (Visual Analogue Scale (VAS) 0-10, high bad) and no recent change in RA med...

BACKGROUND Idiopathic pulmonary fibrosis (IPF) and sarcoidosis impact significantly on health-related quality of life (HRQOL). There are few studies on the impact of patient confidence on HRQOL in these conditions. OBJECTIVES 1. To investigate whether patient confidence is associated with HRQOL, anxiety, depression, dyspnoea or fatigue. 2. To assess if patient confidence is associated with in...