Mechanisms underlying changes in HDL composition caused by obesity are poorly defined, partly because mice lack expression of cholesteryl ester transfer protein (CETP), which shuttles triglyceride and cholesteryl ester between lipoproteins. Because menopause is associated with weight gain, altered glucose metabolism, and changes in HDL, we tested the effect of feeding a high-fat diet (HFD) and ...

The induction of bystander suppression, whereby the response against one Ag is suppressed when it is presented in the context of an Ag to which tolerance is already established, would be an important property of oral tolerance, because it would allow treatment of autoimmune and hypersensitivity responses where the initiating Ag is not known. Although bystander suppression has been described in ...

I read with interest the article by Lewis et al. [1] who presents a review and meta-analysis of randomized controlled trials (RCTs) examining the benefit and harms of prokinetics in patients receiving enteral nutrition. They used the Grading of recommendation, assessment, development, and evaluation (GRADE) method to assess the quality of evidence for various clinical outcomes including feeding...

Background: Autoimmune type 1 diabetes mellitus is caused by T-cell mediated immune destruction of the insulin-producing β-cell in pancreatic islets of Langerhans. Specificity of the auto-antibodies and of the auto-reactive T-cells has been investigated, in which several auto-antigens were proposed. Objective: To determine whether glutamic acid decarboxylase (GAD) feeding would induce oral tol...

BACKGROUND Congenital sucrase-isomaltase deficiency (CSID) is a rare genetic disorder. The prevalence of CSID in Chinese population is unknown and no single case has been reported. METHODS Sucrose tolerance tests were performed in three children suspected of CSID. Glucose tolerance tests were performed to exclude glucose malabsorption. Blood glucose was measured at fasting and at 30 min, 60 m...

 Use of human milk is the preferred food substrate for neonates due to its immunologic properties and better tolerance by the immature GI tract. There is a dose-dependent correlation in the first month of life for reduction of feeding intolerance, nosocomial infection, necrotizing enterocolitis (NEC), chronic lung disease and retinopathy of prematurity compared to formula feeding. (Ronnestad, ...

Theresistance mechanisms exhibited by the five selected maize varieties against Ostrinia furnacalis [Gueene] or Asian corn borer (ACB) were identified and evaluated in study terms of insects’ percent mortality development. The detached leaf-feeding assay was used experiment laid out Complete Randomized Design (CRD) with 5 treatments replicated three times. Findings among tested ACB, Bt had a hi...