The Caliciviridae family of viruses contains clinically important human and animal pathogens, as well as vesivirus 2117, a known contaminant of biopharmaceutical manufacturing processes employing Chinese hamster cells. An extensive literature exists for inactivation of various animal caliciviruses, especially feline calicivirus and murine norovirus. The caliciviruses are susceptible to wet heat...

Feline calicivirus (FCV) is a common viral pathogen found in domestic cats. FCV highly contagious and demonstrates high genetic variability. Upper respiratory tract disease, oral ulcerations, salivation, gingivitis–stomatitis have been regarded as typical clinical signs of infection. Ulcerative dermatitis, abortion, severe pneumonia, enteritis, chronic stomatitis, virulent systemic disease repo...

The Caliciviridae family comprises positive-sense RNA viruses of medical and veterinary significance. In humans, caliciviruses are a major cause of acute gastroenteritis, while in animals respiratory illness, conjunctivitis, stomatitis, and hemorrhagic disease are documented. Investigation of virus-host interactions is limited by a lack of culture systems for many viruses in this family. Feline...

Appropriate interpretation of a positive reverse transcription-PCR is an important issue for virus-related health hazard assessment because viral genomes and infectious viruses exhibit different behavior patterns in water. In this context, using Poliovirus 1 and Feline calicivirus f9 as examples of enteric viruses, first we demonstrated that the stability of infectious viruses is greatly affect...

The focus of coagulation as a water treatment process is shifting to accommodate recent regulatory additions that strive to balance the risks between microbial and chemical contamination of drinking water. In this work, enhanced coagulation using increased ferric chloride dose and/or pH adjustment was evaluated for removal efficacy of viruses on the United States Environmental Protection Agency...

Caliciviruses use reinitiation of translation governed by a 'termination upstream ribosomal binding site' (TURBS) for expression of their minor capsid protein VP2. Mutation analysis allowed to identify sequences surrounding the translational start/stop site of the feline calicivirus (FCV) that fine tune reinitiation frequency. A selection of these changes was introduced into the infectious FCV ...

A serological classification of five feline calicivirus (FCV) strains of Swiss origin and 13 isolates of Austrian origin was attempted. The antisera used had been prepared in rabbits against the five Swiss strains and in goats against six American strains. Homologous and heterologous neutralization tests were made in tube cultures using sera at dilutions that contained 20 antibody units, in una...