Background: Myocardial infarction (MI) is one of the most important causes of death worldwide. The effect of flunixin meglumine (FM) on MI is unknown. We investigated the protective effect of FM on the serum biochemical profile, malondialdehyde (MDA), and heart histology changes induced by isoproterenol (ISO) in adult male rats. Methods: Rats were randomly divided into four groups of six eac...

Matrix metalloproteinase-8 (MMP8) has been shown to influence various cellular functions. As monocytes and macrophages (Mφ) express MMP8, we investigated if MMP8 played a role in macrophage differentiation and polarization. MMP8 expression was significantly increased during monocyte differentiation into Mφ. Monocyte-derived Mφ from MMP8-deficient mice expressed higher levels of M1-Mφ markers bu...

The development of bleomycin-induced pulmonary fibrosis in rats was studied over a period of 21 d after an intratracheal instillation of bleomycin. The expression of three small proteoglycans (biglycan, decorin, and fibromodulin), collagen III and TGF-beta 1 was studied by RNA-transfer blot analysis. The proteoglycans were also studied by SDS-polyacrylamide gel electrophoresis and Western blots...

1. FM-FM neurons in the auditory cortex of the mustached bat are sensitive to a pair of frequency-modulated (FM) sounds that simulates an FM component of the orientation sound and an FM component of the echo. These neurons are tuned to particular delays between the two FM components, suggesting an encoding of target range information. The response properties of these FM-FM neurons, however, hav...

background: the foramen magnum (fm) is an important landmark of the skull base and a transition zone between spine and skull as well as its close relationship to the brain and the spinal cord. so the fm has gained considerable interest due to its comparative anatomy, ontogeny, clinical, and animal breeding viewpoints. objectives: the aim of this study was to determine morphology and morphometry...

In an earlier work [6] we presented a simple FM-index variant, based on the idea of Huffman-compressing the text and then applying the Burrows-Wheeler transform over it. The main drawback of using Huffman was its lack of synchronizing properties, forcing us to supply another bit stream indicating the Huffman codeword boundaries. In this way, the resulting index needed O(n(H0+1)) bits of space b...