Previously we had isolated two prenylated flavanones and two prenylated dihydrochalcones, macatrichocarpins A-D (1-4), from the acetone extract of the leaves of Macaranga trichocarpa. Re-examination of the fractions containing minor components resulted in the isolation of four more flavonoid derivatives, including two new prenylated dihydrochalcones, oxymacatrichocarpin C (5) and isomacatrichoc...

Macaranga triloba belongs to the family of Euphorbiaceae. Investigation on the dichloromethane extract of flower of Macaranga triloba collected at Hulu Terengganu, Malaysia has yielded four flavanone compounds known as 6-prenyl-3’-methoxy-eriodictyol (1), nymphaeol-B (2), nymphaeol-C (3) and 6-farnesyl3’,4’,5,7-tetrahydroxyflavanone (4). The structures of these compounds were elucidated based o...

A irradiação de chalconas com microondas na ausência de solvente se mostrou um procedimento de “química verde” para a preparação, em bons rendimentos, de flavanonas. Diferentes catalisadores heterogêneos e catalisadores convencionais foram testados usando-se um forno de microondas doméstico. A irradiação de chalconas com 30% de ácido trifluoroacético, na presença de gel de sílica, levou a forma...

The demand for skin-whitening agents is high across the world, including Asian countries. An extensive screening using a tyrosinase inhibition assay was performed in order to discover novel plant materials. In our research program investigating safe and effective agent, 50% ethanolic extracts prepared from discarded parts of Prunus persica were screened vitro inhibitory activity. Among tested, ...