Stachys genus with medicinal properties and high polymorphic features has been considered oneof the largest genera of Lamiaceae. The aim of this study was to determine the flavonoid patternvariations and flavonoid groups in ten Stachys species belonging to two sections; Fragilicaulis,and Aucheriana. The studied species were collected from natural habitats in Iran and analysedfor their flavonoid...

High performance liquid chromatography (HPLC) with diode array detection (DAD) and electrospray ionization tandem mass spectrometry (ESI/MS/MS) was used to analyze the main components in the methanol extract of Fructus Aurantii (FA) and the metabolites in rat biological samples after oral administration of the methanol extract of FA. There were 31 constituents identified in the extract of FA in...

Infrared (IR) spectroscopy combined with chemometrics has been developed for simple analysis of flavonoid in the medicinal plant extract. Flavonoid was extracted from medicinal plant leaves by ultrasonication and maceration. IR spectra of selected medicinal plant extract were correlated with flavonoid content using chemometrics. The chemometric method used for calibration analysis was Partial L...

Tribulus terrestris extract has an ancient tradition in folk medicine and in ayurveda as a diuretic, mood enhancer, antiseptic and anti-inflammatory agent. Six populations of Tribulus terrestris were studied in North India at different ecological habitats. Populations have different phenotypes and chemotypes. We detected two main and other flavonoid components of this plant by TLC and HPLC in d...

BACKGROUND Flavonoids inhibit the growth of colon cancer cells in vitro. In a secondary analysis of a randomized controlled trial, the Polyp Prevention Trial, a higher intake of one subclass, flavonols, was statistically significantly associated with a reduced risk of recurrent advanced adenoma. Most previous prospective studies on colorectal cancer evaluated only a limited number of flavonoid ...

The glycosylation of flavonoids increases their solubility and stability in plants. Flowers accumulate anthocyanidin and flavonol glycosides which are synthesized by UDP-sugar flavonoid glycosyltransferases (UFGTs). In our previous study, a cDNA clone (Fh3GT1) encoding UFGT was isolated from Freesia hybrida, which was preliminarily proved to be invovled in cyanidin 3-O-glucoside biosynthesis. H...

Epidemiological studies have suggested that flavonoids exhibit preventive effects on degenerative diseases. However, lack of sufficient data on flavonoid intake has limited evaluating the proposed effects in populations. Therefore, we aimed to estimate the total and individual flavonoid intakes among Korean adults and determine the major dietary sources of these flavonoids. We constructed a fla...

BACKGROUND Flavonoid metabolites remain in blood for periods of time potentially long enough to allow interactions with cellular components of this tissue. It is well-established that flavonoids are metabolised within the intestine and liver into methylated, sulphated and glucuronidated counterparts, which inhibit platelet function. METHODOLOGY/PRINCIPAL FINDINGS We demonstrate evidence sugge...

Plants of Euphorbiaceae are used to cure various diseases in traditional systems of medicine. For present study, Homonoia riparia, Kirganelia reticulata, Phyllanthus fraternus and Pedilanthus tithymaloides were selected on the basis of their availability and antimicrobial activity. Plant phenolics and flavonoids are known to possess antioxidant activity. Hence, it was decided to evaluate the an...