Studies of psychopharmacology often use the test of the critical flicker fusion (CFF) threshold as a measure of total information processing. It is true that studies of practice effects have shown that CFF thresholds are remarkably stable within and across multiple days of testing. This study confirms that subjects who undergo CFF testing on sequential days have stable thresholds, but also demo...

Background: Computer usage has rapidly grown. This is because it helps to resolve problems, i.e., encountered in daily life by individuals. Various monitor screens that have been developed affect the userchr('39')s eyes. Screen size is one of the relevant impacts. Thus, this study compared the immediate effects of two computer screen sizes on visual fatigue in Video Display Terminal (VDT) users...

Critical fusion frequency (CFF) of toad rods was examined at various intensities using intracellular recordings. Data were compared to CFF measurements (as a function of intensity) obtained with the electroretinogram (ERG) and with a horizontal cell. In all instances the rod (and rod mediated) responses produced a curve which increased monotonically to a high frequency asymptote at about 6 Hz. ...

2562-Pos Board B254 Direct Detection of Reconstituted, Snare-Mediated Fusion Pore Dynamics Zhenyong Wu, Erdem Karatekin. Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA. Exocytosis underlies release of neurotransmitters and hormones. Electrophysiological and electrochemical measurements from live cells have shown that the initial fusion pore is small (~1 nm ...

The formation of the fusion pore is the first detectable event in membrane fusion (Zimmerberg, J., R. Blumenthal, D.P. Sarkar, M. Curran, and S.J. Morris. 1994. J. Cell Biol. 127:1885-1894). To date, fusion pores measured in exocytosis and viral fusion have shared features that include reversible closure (flickering), highly fluctuating semistable stages, and a lag time of at least several seco...

BACKGROUND An efficacious, reliable, and non-invasive route of administration for midazolam, a drug used for sedation and pre-anaesthetic medication, would have obvious advantages. This study compares two potential methods of administering midazolam by the nasal and nebulized routes. METHODS Midazolam (0.2 mg kg(-1)) was given by both nebulizer and nasally by liquid instillation to 10 healthy...

AIM The present study investigates the effect of combined treatment with Ginkgo biloba and/or Rhodiola rosea on psychomotor vigilance task (PVT) and short-term working memory accuracy. SUBJECTS AND METHODS A total number of 112 volunteers were enrolled to study the effect of G. biloba and R. rosea on PVT and short-term working memory accuracy as compared to placebo effects, the central cognit...

In this paper, a method based on continuous wavelet transform is suggested for calculation of flicker power. The flicker power can be utilized to identify the flicker direction to a flicker source with respect to a monitoring point. In our proposed method, using continuous Gaussian wavelet transform, pure flicker waveforms are extracted from the measured voltage and current signals. The flicker...