We have generated transgenic mice that constitutively express murine interleukin (IL)-5 in the lung epithelium. Airway expression of this cytokine resulted in a dramatic accumulation of peribronchial eosinophils and striking pathologic changes including the expansion of bronchus-associated lymphoid tissue (BALT), goblet cell hyperplasia, epithelial hypertrophy, and focal collagen deposition. Th...

Benign liver tumors are common in general population, can be seen in 9% to 20% of individuals. Some of these tumors have a completely benign natural history and do not need to be resected, while others carry a risk of growth, hemorrhage, or malignant transformation and should be operatively removed. Obtaining a preoperative diagnosis is therefore critical, and this single factor remains the pri...

INTRODUCTION Computed tomography and magnetic resonance imaging are able to demonstrate and to diagnose hepatic focal nodular hyperplasia when a typical pattern of a well-circumscribed lesion with a central scar is present.Our aim is to propose the split-bolus multidetector-row computed tomography technique as an alternative to the conventional triphasic technique in the detection and character...

4 Glycosaminoglycans were inyestigated in surgically removed human liver and kidney tumours by applying biochemical methods. Four liver adenoma, 6 focal nodular hyperplasia and 9 primary hepatocellular carcinoma samples were compared with nermal liyer frorn autopsy cases and also with liyer tissue adjacent to PHC. The studies on kidney included 14 renal cell carcinoma and 4 wilms' tumour sample...

A 25 year old healthy female presented with a two month history of nausea, epigastric pain that worsened after eating and diarrhea. Complete blood count and biochemistry panel results were unremarkable and liver serology was negative. Abdominal ultrasonography (US) showed a solid lesion in the right upper quadrant, suspicious for a gastric mass. Liver protocol multiphase computed tomography (CT...

Liver cell adenoma and focal nodular hyperplasia are benign conditions, often encountered in young and middle aged female patients. They can present acutely, but more often are diagnosed incidentally during investigation of abnormal liver function tests or vague abdominal pain. We present four cases, which contrast the diagnosis and management of focal nodular hyperplasia (FNH) and liver cell a...