Native disulfide bond formation is critical for the proper folding of many proteins. Recent studies using newly identified protein oxidants, folding catalysts, and mutant cells provide insight into the mechanism of oxidative protein folding in vivo. This insight promises new strategies for more efficient protein production.

We show a novel design method of one-DOF deployable mechanism based on a space curve, through creating a curved folding and discretizing the folding into rigid origami. By interpreting constant angle curved folding as a flat-foldable quadrilateral mesh origami, we design novel irregular tessellated, cylindrical, and cellular flatly collapsible structures, whose behavior is easily controlled by ...

In an attempt to explore the understanding of protein folding mechanism, various models have been proposed in the literature. Advances in recent experimental and computational techniques rationalized our understanding on some of the fundamental features of the protein folding pathways. The goal of this review is to revisit the various models and outline the essential aspects of the folding reac...