By studying the pressure dependence of the fragility, it is expected that new horizons will open to understand the relaxation behaviour of supercooled liquids. However, as far as the authors are informed, no study has been performed on pressure dependence of the fragility in bulk metallic glass forming systems. In the present study, such dependence is investigated based on materials properties ...

Erythrocytes containing haemoglobin C do not lyse normally in the peroxidase channel of the Technicon H6000 automated cell counter. This interferes with the normal function of the channel and results in a characteristic abnormal pattern. This correlates with a reduced osmotic fragility of the red cells.

background: the capacity of human hbaa erythrocytes of non-malarious blood to withstand osmotic stress in the presence of five antimalarial drugs, chloroquine phosphate, quinine, fansidartm, coartemtm and halfantm was studied in vitro. materials and methods: aqueous solutions of four increasing concentrations of the drugs used in this investigation were in the order: 0.2%, 0.4%, 0.6% and 0.8% (...

Growth, History, or Institutions? What Explains State Fragility in Sub-Saharan Africa We explore the determinants of state fragility in sub-Saharan Africa. Controlling for a wide range of economic, demographic, geographic and istitutional regressors, we find that institutions, and in particular the civil liberties index and the number of revolutions, are the main determinants of fragility, even...

Specialized topoisomerases solve the topological constraints arising when replication forks encounter transcription. We have investigated the contribution of Top2 in S phase transcription. Specifically in S phase, Top2 binds intergenic regions close to transcribed genes. The Top2-bound loci exhibit low nucleosome density and accumulate gammaH2A when Top2 is defective. These intergenic loci asso...

Recent tsunami events have stimulated research activity into tsunami fragility functions which have been largely based on empirical data. However, empirical fragility functions are biased because the influence of earthquake and tsunami damage are difficult to separate. We develop a new theoretical framework to assess the structural performance of a building due to tsunami inundation by drawing ...

acute fulminant myocarditis is a life-threatening inflammatory disease of the myocardium characterized by the rapid deterioration of the hemodynamic status of the affected individual. with prompt recognition and appropriate management, complete recovery of ventricular function is likely within a few weeks. we introduce a 28-year-old man with acute fulminant myocarditis, who experienced circulat...

recently, two of the authors have introduced the collapse capacity spectrummethodology, which allows the assessment of the collapse capacity of highly inelastic p-deltasensitive regular frame structures without performing non-linear time-history analyses. the mainingredient of this method is the collapse capacity spectrum, which represents the seismic collapsecapacity of an inelastic non-deteri...

Fragility curves are very useful in quantifying the physical and economic damage of buildings that have undergone an earthquake. This paper presents the development of analytical fragility curves representative of mid-rise residential structures built with reinforced concrete, taking into account the specific structural characteristics of Algerian buildings. The derivation of the analytical fra...

Although it is recognized that red cells lose membrane during storage, estimation of the osmotic fragility of erythrocytes has not previously proven to be a useful measurement of the storage lesion. Erythrocytes from blood stored in CPD-A2 were found to have a markedly increased osmotic fragility. A major portion of this increase was found to be due to accumulation of lactate, which is only slo...