BACKGROUND Nausea and vomiting of pregnancy (NVP) affects up to 80% of expecting mothers. In April 2013 the FDA approved the delayed-release combination of doxylamine succinate and pyridoxine hydrochloride (Diclegis®) for NVP, based in part, on the results of a phase III randomized trial demonstrating the efficacy of this drug combination [study drug marketed under the trade name Diclectin® in ...

OBJECTIVE Parasites may recur asymptomatically after initial clearance by antimalarial treatment. Current guidelines recommend treatment only when patients develop symptoms or at the end of follow-up. We wanted to assess prospectively the probability of becoming symptomatic and the risks of this practice. METHODS We analysed data collected in 13 trials of uncomplicated paediatric malaria cond...

Serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin (PRL) levels were examined during consecutive reproductive states in Mongolian gerbils. The results indicate that FSH, LH, and PRL levels peak at proestrus, estrus, and diestrus, respectively. During early gestation in primiparous gerbils, gonadotropin levels were the lowest on day 6. This was followed by an incre...

The 7th annual Global Handwashing Day will be observed October 15, 2014. This observance increases awareness and understanding of handwashing with soap as an effective and affordable way to prevent disease around the world. Handwashing with soap has an important role to play in child survival and health. Approximately 2.2 million children aged <5 years die each year from diarrheal diseases and ...

the present article is aimed at study on agroclimatic conditions of cultivation of sunflower throughout selected substations at kurdistan  province by means of gis system. in this investigation, meteorological data have been received from synoptic stations based on daily, monthly, and annually trend from iran meteorological organization (imo) at kurdistan  province and then homogeneity of data ...

October 12, 2017 is World Arthritis Day (http://www. worldarthritisday.org). First observed in 1996, World Arthritis Day serves as a focus for organizations and individuals to work toward increasing awareness of arthritis and other rheumatic conditions worldwide. In the United States, 54 million adults (1) have some form of arthritis or other rheumatic condition. By 2040, the number of adults w...

OBJECTIVE Autophagy is activated in ischemic heart diseases, but its dynamics and functional roles remain unclear and controversial. In this study, we investigated the dynamics and role of autophagy and the mechanism(s), if any, during postinfarction cardiac remodeling. METHODS AND RESULTS Acute myocardial infarction (AMI) was induced by ligating left anterior descending (LAD) coronary artery...