Introduction. Associations of disturbances in innate and adaptive immunity during the clinical course schizophrenia have been found a number studies. Yet, relationship immune parameters systemic inflammation relation to disease its prognosis, remains poorly understood, which highlights an interesting topic for further research. The goal this study was research immuno-inflammatory changes patien...

BACKGROUND Quality of life (QoL) is the sense of well-being perceived by people. The improvement of parkinsonian patient's QoL is a crucial goal for clinicians involved in rehabilitative care. In order to provide an appropriate endpoint for the assessment of the effectiveness of rehabilitation treatments on QoL of patients with Parkinson's Disease (PD), in this study we have first translated an...

Alcohol abuse can impact on general cognitive functioning and more particularly on frontal lobe functions. One option available to reduce this impact may rest on rehabilitation paradigms that include cognitive stimulation programmes. This paper reports on a randomized controlled study where two sample of patients with alcohol dependence syndrome where enrolled: 1) on a mHealthbased cognitive st...

The Cognitive section of the Alzheimer's Disease Assessment Scale (ADAS-Cog) remains the most widely used cognitive measure in dementia trials although it does not assess attention, executive function, or agnosia. Designed for use in Alzheimer's disease (AD), it may not be ideal in assessing patients with other diagnoses. The ADAS-Cog differentiates between AD patients, patients with Mild Cogni...

Background The priority problem of modern healthcare is irreversible dementia due to the steady increase in morbidity. Among dementias, Alzheimer’s disease takes first place. Most often, only with sufficiently pronounced cognitive disorders, doctor can diagnose disease, although it obvious that neurodegenerative process begins even before clinical manifestations disease. Due common origin eye a...

Background Accumulated evidence suggests altered energy metabolism in the brain of tauopathies. In Alzheimer’s disease (AD) and progressive supranuclear palsy (PSP), decreased fluorodeoxyglucose (FDG) uptake cingulate cortex is considered a marker neurodegeneration. However, its underlying pathogenesis remains unknown. It hypothesized that lactate, glucose metabolite, produced astrocytes subseq...

OBJECTIVE To describe and compare diffusion tensor imaging (DTI) parameters between patients with subcortical ischemic vascular disease (SIVD) and Alzheimer's disease (AD) diagnosed using structuralized neuropsychiatric assessments, and investigate potential neuronal substrates related to cognitive performance. METHODS Thirty-five patients with SIVD, 40 patients with AD, and 33 cognitively no...