Regulatory focus theory identifies two separate motivational systems, promotion and prevention, that fulfill different regulatory needs and are differentially related to approach and avoidance. In the psychophysiological literature, approachand avoidancerelated emotions and motivational orientations have been linked to asymmetries in frontal cortical activity. In an effort to synthesize these l...

Age is known to affect prefrontal brain structure and executive functioning in healthy older adults, patients with neurodegenerative conditions and TBI. Yet, no studies appear to have systematically investigated the effect of age on cognitive performance in patients with focal lesions. We investigated the effect of age on the cognitive performance of a large sample of tumour and stroke patients...

The solution of chemical process engineering problems often requires the repeated solution of large sparse linear systems of equations that have a highly asymmetric structure. The frontal method can be very e cient for solving such systems on modern computer architectures because, in the innermost loop of the computation, the method exploits dense linear algebra kernels, which are straightforwa...

We used the activation likelihood estimation (ALE) method to quantitatively synthesize data from 19 published brain mapping studies of phonological processing in reading, six with Chinese and 13 with alphabetic languages. It demonstrated high concordance of cortical activity across multiple studies in each written language system as well as significant differences of activation likelihood betwe...

Everyday circumstances require efficient updating of behavior. Brain systems in the right inferior frontal cortex have been identified as critical for some aspects of behavioral updating, such as stopping actions. However, the precise role of these neural systems is controversial. Here we examined how the inferior frontal cortex updates behavior by combining reversible cortical interference (tr...

OBJECTIVE Interhemispheric and intrahemispheric balance models may be integrated to gain an increased understanding of how cerebral systems are involved in the regulation of heart rate and blood pressure. We sought to examine the relationship between left and right frontal and posterior activity and resting heart rate and blood pressure. Based on this integration, we predicted that lateral (lef...