A Cl- current (ICl) induced by isoproterenol (ISO) has been identified in isolated guinea pig ventricular myocytes. This ISO-induced ICl can be inhibited by propranolol and mimicked by forskolin (FSK), suggesting that beta-receptors, cAMP, and protein kinase A (PKA) are involved in regulating the involved Cl- channel. Because activation of protein kinase C (PKC) mediated via alpha-adrenergic re...

This paper describes the design of a programmable FSK-modulator based on VCO and its implementation in 0.35m CMOS process. The circuit is used to transmit digital data at 100Kbps rate in the frequency range of 400-600MHz. The design and operation of the modulator is discussed briefly. Further the characteristics of PLL, frequency synthesizer, VCO and the whole design are elaborated. The variati...

We describe a transmission scheme combining 4-FSK modulation with diversi&'&d coding to make the transmission over power lines robust against permanent frequency disturbances and impulse noise. We use simple non-coherent detection and derive the corresponding error correcting capabilities of the scheme. Since we use 4-FSK, the scheme is in agreement with the existing CENELEC norms. The scheme c...

In this paper we studied the performance of an STOLAS project based node switching an FSK/IM modulated signal. A simulation model for 10Gbit/s IM modulated payload FSK labelled at 155Mbit/s, of an optical label switching node, has been developed. The performance of a single node, the effect of the crosstalk between channels and the impact of the extinction ratio value of the IM signal on the ov...

Direct discrimination of FM and FSK optical signals using injection-locked DFB semiconductor lasers is analysed. The demodulation eficiency is found to be independent of the optical injection level in the steady state. However, the optical injection level is important in determining the dynamic response. There exists an optimum optical injection rate to achieve the highest demodulation speed. T...

Eric K. Hall and Stephen G. Wilson University of Virginia Charlottesville, VA 22903 Abstract In this work, the application of turbo codes to communications systems using noncoherent FSK and DPSK is considered for the AWGN channel. For both cases, the turbo decoder is formulated employing the appropriate channel metrics. For DPSK, a Gaussian metric is formed while FSK utilizes two decision stati...

Contractile stimuli can sensitize myosin to Ca2+ by activating RhoA kinase (ROK) and PKC that inhibit myosin light chain phosphatase (MLCP) activity. Relaxant stimuli, acting through PKA and PKG (cyclic nucleotide-dependent protein kinases), and pretreatment with contractile agents such as phenylephrine (PE), can desensitize myosin to Ca2+. It is unknown precisely how these stimuli cause Ca2+ d...