The Gcn5-related N-acetyltransferases (GNATs) are ubiquitously expressed in nature and perform a diverse range of cellular functions through the acetylation of small molecules and protein substrates. Using activated acetyl coenzyme A as a common acetyl donor, GNATs catalyse the transfer of an acetyl group to acceptor molecules including aminoglycoside antibiotics, glucosamine-6-phosphate, histo...

GCN5-related N-acetyltransferases (GNATs) are the most widely distributed acetyltransferase systems among all three domains of life. GNATs appear to be involved in several key processes, including microbial antibiotic resistance, compacting eukaryotic DNA, controlling gene expression, and protein synthesis. Here, we report the crystal structure of a putative GNAT Ta0374 from Thermoplasma acidop...

The relationships among the genera of fungus gnats in mycetophilid subfamily Leiinae are unclear, and monophyly this group is questionable. This monograph provides an extensive phylogenetic study based on morphological data from a large taxonomic sample, including all that have ever been assigned to wide outgroup sampling properly test subfamilial monophyly. A matrix with 128 features 117 termi...

A well-controlled growth environment with plants that are not unduly stressed is essential for Arabidopsis molecular biology research. Even if they do not kill the plants outright, insect pests and microbial pathogens can cause subtle changes in gene expression or plant metabolism that affect experimental results. Therefore, regular scouting for infestations, frequent cleaning of plant growth a...

Dalotia coriaria (Kraatz) (Coleoptera: Staphylinidae) and entomopathogenic nematodes (Rhabditida: Heterorhabditidae and Steinernematidae) are two soil-dwelling biological control agents used to manage western flower thrips, Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae) and fungus gnats Bradysis spp. (Diptera: Sciaridae) in glasshouses. Growers often use multiple natural enemie...