OBJECTIVE To identify medications and other potential risk factors, in addition to renal dysfunction, for developing gadolinium-induced nephrogenic systemic fibrosis (NSF). DATA SOURCES Information was obtained from PubMed, International Pharmaceutical Abstracts, Iowa Drug Information Service, and Google Scholar, using the unlimited search terms nephrogenic systemic fibrosis, NSF, nephrogenic...

The current study aims to explore how the gadolinium (Gd)-based contrast agent (GBCA) Omniscan® enhanced cell viability of murine fibroblasts. The results of scanning electron microscopy showed that Omniscan® can precipitate in cell culture media and deposit on cell membranes. Energy-dispersive X-ray analysis and Fourier-transform infrared spectroscopy demonstrated the presence of Gd and phosph...

many farmers periodically use deep tillage operations to alleviate compaction in the soil profile caused by natural factors or machinery traffic. in 2012 and 2013, a study was initiated in the pannonian region of croatia to study the effects of no-tillage (nt), conventional tillage (ct) and deep tillage (dt) on soil compaction, measured by (bd), soil water content (swc), penetration resistance ...

Distinctive thymidine (dT) kinase molecular forms are present in mouse, human, and monkey mitochondria. Disk polyacrylamide gel electrophoresis (disk PAGE) analyses have shown that the mitochondrial-specific dT kinases differ from cytosol dT kinases in relative electrophoretic mobilities (Rm). Furthermore, the mouse mitochondrial dT kinase differs in Rm value from primate mitochondrial dT kinas...

several mri contrast agents (cas) are used in medical diagnosis that gadolinium (gd3+) is the most widely used as contrast agents. unfortunately, its toxicity is due to its inefficiency. in this review, we discuss about the ability of spions in mri and application in multiple sclerosis diagnosis. superparamagnetic iron oxide nanoparticles (spions) such as magnetite nanoparticles are used as goo...

the mass transfer performance of a pulsed disc and doughnut column for extraction of samarium and gadolinium from aqueous nitrate solution with d2ehpa was investigated. the effects of operating parameters such as pulsation intensity, continuous and dispersed phase velocities on column performance were investigated. the axial dispersion model was used to obtain the overall mass transfer coeffici...

Myocardial relaxation is an important energy-dependent process. Hypoxia, unlike ischemia, has not been shown to impair myocardial relaxation. This difference may be because (a) the traditional index to assess isometric muscle relaxation (half time to relaxation or RT((1/2))) reflects both changes in developed tension as well as relaxation and (b) the relaxation process is highly sensitive to te...

Gadolinium chelates, intended as intravenous contrast media for magnetic resonance imaging, have been regarded as nonnephrotoxic and recommended to replace iodinated contrast media in patients with azotemia who are undergoing digital subtraction angiography (DSA). High intraarterial doses (up to 220 mmol of gadodiamide) have been used, with a 40% incidence of nephropathy. The authors discourage...

UNLABELLED Very little is known about processes which are leading to the development of new multiple sclerosis (MS) plaques. Therefore, the problem of correlating immunological disequilibrium in MS patients with the onset of a relapse and with other markers of the disease seems to be of great importance. In our studies we have evaluated the mononuclear subsets in the peripheral blood of multipl...

INTRODUCTION AND OBJECTIVES Biventricular arrhythmogenic cardiomyopathy and left dominant arrhythmogenic cardiomyopathy forms had recently been included in the spectrum of arrhythmogenic cardiomyopathy. The aim of the study was to describe, using cardiovascular magnetic resonance, the patterns of ventricular involvement as well as late gadolinium enhancement in these conditions. METHODS Medic...