that the gallium activity was located near the stomach. After another glass of water was taken, the stomach was imaged again, using the upper three gallium peaks and thus excluding the Tc99m energy. This showed that the gallium activity was no longer present in the stomach (Fig. I). Gallium and Tc-99m were seen on the oscilloscope to enter the small bowel. An image taken 30 min later did not sh...

Abstract Introduction This study aimed to assess whether combination modality imaging (CT, and/or Technetium/Gallium) had any additional benefits over single (CT) in the management of malignant otitis externa (MOE). Method A six-year retrospective case-controlled series was performed including 73 patients presenting with a potential diagnosis MOE. Results CT undertaken 69/73 patients, and these...

The extractabilities of aluminium(III), gallium(III), and indium(III) from hydrochloric acid solutions were investigated using a mixture of two protic ionic liquids, trioctylammonium bis(trifluoromethanesulfonyl)amide ([TOAH][NTf(2)]) and trioctylammonium nitrate ([TOAH][NO(3)]). At a HCl concentration of 4 mol L(-1) or more, gallium(III) was nearly quantitatively extracted and the extractabil...

Gallium is a group IIIa metal that has efficacy in the therapy of malignant disorders such as lymphoma and urothelial tract tumors. Preclinical studies also indicate a role for gallium in autoimmune disorders, suggesting that gallium is able to modulate T-cell immune reactivity. The purpose of this study was to examine the in vitro and in vivo immunomodulatory action of gallium on T-cell functi...

BACKGROUND The management of patients with relapsed or refractory Hodgkin's lymphoma who achieve less than a partial response to first-line salvage chemotherapy is unclear. The objective of this study was to evaluate response and outcomes to second-line salvage and autologous stem cell transplantation in patients not achieving a complete or partial response to platinum-containing first-line sal...

BACKGROUND In patients with Hodgkin's disease, the use of gallium-67 scintigraphy (Ga-67) compared to conventional staging and restaging techniques is still controversial. In particular, in a combined modality treatment with chemotherapy and radiotherapy given in sequence, its role in detecting active disease after chemotherapy may be useful in planning the subsequent radiotherapeutic strategy....

Effect of gallium nitrate on the pharmacokinetics and tissue accumulation of 67Ga was investigated in rats bearing turpentine oil-induced abscess. Gallium nitrate accelerated the blood disappearance of 67Ga, but this effect was less potent than that of ferric nitrate. The accumulation of 67Ga in liver was significantly lowered by gallium nitrate, but no significant decrease of 67Ga accumulation...

Background: In addition to determining the exact tumor location and its geometric features, an increase of the effective tumor atomic number will enhances the chance in treating the tumoral cells under suitable radiation. In the present study, we assessed metrezoate-labeled gallium transmission in Burkett lymphatic cells. Materials and Methods: Human Burkitt lymphatic cells were grown ...

Earlier studies have shown that transferrin-gallium inhibits cellular iron incorporation and blocks DNA synthesis by decreasing the activity of the iron-dependent M2 subunit of ribonucleotide reducÃ-ase.We ex amined the growth-inhibitory effects of gallium nitrate in combination with clinically relevant inhibitors of ribonucleotide reducÃ-asefludarabine (an Ml subunit inhibitor), and iron chela...