نتایج جستجو برای: gamma ring

تعداد نتایج: 244692  

Journal: :EMBO reports 2009
Katsumi Fumoto Moe Kadono Nanae Izumi Akira Kikuchi

Axin is known to have an important role in the degradation of beta-catenin in the Wnt pathway. Here, we reveal a new function of Axin at the centrosome. Axin was localized to the centrosome in various cell lines and formed a complex with gamma-tubulin. Knockdown of Axin reduced the localization of gamma-tubulin and gamma-tubulin complex protein 2-components of the gamma-tubulin ring complex-to ...

Journal: :Physical review letters 2006
B Aubert R Barate D Boutigny F Couderc Y Karyotakis J P Lees V Poireau V Tisserand A Zghiche E Grauges A Palano M Pappagallo A Pompili J C Chen N D Qi G Rong P Wang Y S Zhu G Eigen I Ofte B Stugu G S Abrams M Battaglia A B Breon D N Brown J Button-Shafer R N Cahn E Charles C T Day M S Gill A V Gritsan Y Groysman R G Jacobsen R W Kadel J Kadyk L T Kerth Yu G Kolomensky G Kukartsev G Lynch L M Mir P J Oddone T J Orimoto M Pripstein N A Roe M T Ronan W A Wenzel M Barrett K E Ford T J Harrison A J Hart C M Hawkes S E Morgan A T Watson M Fritsch K Goetzen T Held H Koch B Lewandowski M Pelizaeus K Peters T Schroeder M Steinke J T Boyd J P Burke N Chevalier W N Cottingham T Cuhadar-Donszelmann B G Fulsom C Hearty N S Knecht T S Mattison J A McKenna A Khan P Kyberd M Saleem L Teodorescu A E Blinov V E Blinov A D Bukin V P Druzhinin V B Golubev E A Kravchenko A P Onuchin S I Serednyakov Yu I Skovpen E P Solodov A N Yushkov D Best M Bondioli M Bruinsma M Chao S Curry I Eschrich D Kirkby A J Lankford P Lund M Mandelkern R K Mommsen W Roethel D P Stoker C Buchanan B L Hartfiel A J R Weinstein S D Foulkes J W Gary O Long B C Shen K Wang L Zhang D del Re H K Hadavand E J Hill D B Macfarlane H P Paar S Rahatlou V Sharma J W Berryhill C Campagnari A Cunha B Dahmes T M Hong M A Mazur J D Richman W Verkerke T W Beck A M Eisner C J Flacco C A Heusch J Kroseberg W S Lockman G Nesom T Schalk B A Schumm A Seiden P Spradlin D C Williams M G Wilson J Albert E Chen G P Dubois-Felsmann A Dvoretskii D G Hitlin J S Minamora I Narsky T Piatenko F C Porter A Ryd A Samuel R Andreassen G Mancinelli B T Meadows M D Sokoloff F Blanc P Bloom S Chen W T Ford J F Hirschauer A Kreisel U Nauenberg A Olivas W O Ruddick J G Smith K A Ulmer S R Wagner J Zhang A Chen E A Eckhart A Soffer W H Toki R J Wilson Q Zeng D Altenburg E Feltresi A Hauke B Spaan T Brandt J Brose M Dickopp V Klose H M Lacker R Nogowski S Otto A Petzold J Schubert K R Schubert R Schwierz J E Sundermann D Bernard G R Bonneaud P Grenier S Schrenk Ch Thiebaux G Vasileiadis M Verderi D J Bard P J Clark W Gradl F Muheim S Playfer Y Xie M Andreotti V Azzolini D Bettoni C Bozzi R Calabrese G Cibinetto E Luppi M Negrini L Piemontese F Anulli R Baldini-Ferroli A Calcaterra R de Sangro G Finocchiaro P Patteri I M Peruzzi M Piccolo A Zallo A Buzzo R Capra R Contri M Lo Vetere M Macri M R Monge S Passaggio C Patrignani E Robutti A Santroni S Tosi G Brandenburg K S Chaisanguanthum M Morii E Won J Wu R S Dubitzky U Langenegger J Marks S Schenk U Uwer G Schott W Bhimji D A Bowerman P D Dauncey U Egede R L Flack J R Gaillard J A Nash M B Nikolich W Panduro Vazquez X Chai M J Charles W F Mader U Mallik A K Mohapatra V Ziegler J Cochran H B Crawley V Eyges W T Meyer S Prell E I Rosenberg A E Rubin J Yi N Arnaud M Davier X Giroux G Grosdidier A Höcker F Le Diberder V Lepeltier A M Lutz A Oyanguren T C Petersen S Plaszczynski S Rodier P Roudeau M H Schune A Stocchi G Wormser C H Cheng D J Lange M C Simani D M Wright A J Bevan C A Chavez I J Forster J R Fry E Gabathuler R Gamet K A George D E Hutchcroft R J Parry D J Payne K C Schofield C Touramanis C M Cormack F Di Lodovico W Menges R Sacco C L Brown G Cowan H U Flaecher M G Green D A Hopkins P S Jackson T R McMahon S Ricciardi F Salvatore D Brown C L Davis J Allison N R Barlow R J Barlow C L Edgar M C Hodgkinson M P Kelly G D Lafferty M T Naisbit J C Williams C Chen W D Hulsbergen A Jawahery D Kovalskyi C K Lae D A Roberts G Simi G Blaylock C Dallapiccola S S Hertzbach R Kofler V B Koptchev X Li T B Moore S Saremi H Staengle S Willocq R Cowan K Koeneke G Sciolla S J Sekula M Spitznagel F Taylor R K Yamamoto H Kim P M Patel S H Robertson A Lazzaro V Lombardo F Palombo J M Bauer L Cremaldi V Eschenburg R Godang R Kroeger J Reidy D A Sanders D J Summers H W Zhao S Brunet D Côté P Taras B Viaud H Nicholson N Cavallo G De Nardo F Fabozzi C Gatto L Lista D Monorchio P Paolucci D Piccolo C Sciacca M Baak H Bulten G Raven H L Snoek L Wilden C P Jessop J M Losecco T Allmendinger G Benelli K K Gan K Honscheid D Hufnagel P D Jackson H Kagan R Kass T Pulliam A M Rahimi R Ter-Antonyan Q K Wong J Brau R Frey O Igonkina M Lu C T Potter N B Sinev D Strom J Strube E Torrence F Galeazzi M Margoni M Morandin M Posocco M Rotondo F Simonetto R Stroili C Voci M Benayoun H Briand J Chauveau P David L Del Buono Ch de la Vaissière O Hamon M J J John Ph Leruste J Malclès J Ocariz L Roos G Therin P K Behera L Gladney Q H Guo J Panetta M Biasini R Covarelli S Pacetti M Pioppi C Angelini G Batignani S Bettarini F Bucci G Calderini M Carpinelli R Cenci F Forti M A Giorgi A Lusiani G Marchiori M Morganti N Neri E Paoloni M Rama G Rizzo J Walsh M Haire D Judd D E Wagoner J Biesiada N Danielson P Elmer Y P Lau C Lu J Olsen A J S Smith A V Telnov F Bellini G Cavoto A D'Orazio E Di Marco R Faccini F Ferrarotto F Ferroni M Gaspero L Li Gioi M A Mazzoni S Morganti G Piredda F Polci F Safai Tehrani C Voena H Schröder G Wagner R Waldi T Adye N De Groot B Franek G P Gopal E O Olaiya F F Wilson R Aleksan S Emery A Gaidot S F Ganzhur G Graziani G Hamel de Monchenault W Kozanecki M Legendre G W London B Mayer G Vasseur Ch Yèche M Zito M V Purohit A W Weidemann J R Wilson F X Yumiceva T Abe M T Allen

A search for the nonconservation of lepton flavor in the decay tau+/--->e+/-gamma has been performed with 2.07x10(8) e+e--->tau+tau- events collected by the BABAR detector at the SLAC PEP II storage ring at a center-of-mass energy near 10.58 GeV. We find no evidence for a signal and set an upper limit on the branching ratio of Beta(tau+/--->e+/-gamma)<1.1x10(-7) at 90% confidence level.

2012

Gamma-hydroxybutyrate / butyric acid, ambiguously called GHB, presents some unique challenges for analysis due in part to its acidity, high polarity, and high solubility in aqueous solution. Its chemistry is complicated by its conversion into the corresponding lactone compound, where the GHB molecule condenses to form a cyclic ester with a five-membered ring. This compound, gamma-butyrolactone ...

Journal: :Current Biology 1996
Steven M Murphy Tim Stearns

The centrosomal protein gamma-tubulin is part of a ring-shaped complex that can induce microtubule polymerization. This complex may explain how the centrosome nucleates microtubule polymerization, and thereby organizes the microtubule cytoskeleton.

2015
Ramesh Ahirwar

Mutagenic effectiveness of gamma rays on Allium cepa was studied. The seeds were treated with five doses (viz. 5kR, 10kR, 15 kR, 20kR and 25kR) of gamma rays. Chromosomal abnormalities were observed. Chromosomal aberrations like, dicentric, tricentric, ring, minute, deletion, fragment, laggard, bridge and micronuclei were noticed in treated root tip mitosis. The chromosomal abnormalities were i...

Journal: :Carbohydrate research 2009
Evelyn Paz-Morales Ruth Melendres Fernando Sartillo-Piscil

A seven-step total synthesis of Hagen's gland lactones 1 and 2 starting from 1,2-O-isopropylidene-alpha-D-xylofuranose 3 is reported. The success of this short and practical synthesis depends on the use of two key reactions: a stereoselective nucleophilic substitution at the anomeric position of 5 and 6, which allowed the construction of the gamma-lactone ring, and an alkyl substitution reactio...

Journal: :Bioscience, biotechnology, and biochemistry 2010
Hiroyuki Urano Masaru Enomoto Shigefumi Kuwahara

A new enantioselective total synthesis of pachastrissamine (jaspine B) was achieved from a known alpha,beta-unsaturated aldehyde by utilizing Córdova's asymmetric epoxidation as the chirality-inducing step. The 2,3-cis stereochemistry of pachastrissamine was established via intramolecular epoxide ring opening of a gamma,delta-epoxy-alpha,beta-unsaturated ester intermediate coupled with oxy-Mich...

Journal: :Bioorganic & medicinal chemistry 2009
Kenneth N Mewett Sebastian P Fernandez Anmol K Pasricha Alice Pong Steven O Devenish David E Hibbs Mary Chebib Graham A R Johnston Jane R Hanrahan

We herein describe the synthesis and positive modulatory activities of a small library of flavan-3-ol derivatives on alpha(1)beta(2)gamma(2L) GABA(A) receptors. Structure-activity relationships of various substituents on the A, B and C rings were evaluated in a functional electrophysiological assay. A trans configuration and a 3-acetoxy moiety are essential for activity. Substitution of the B r...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1985
C J Chetsanga C Grigorian

When aqueous solutions of DNA were treated with 10-500 grays of gamma-rays, the imidazole rings of some adenine and guanine residues underwent scission, resulting in the conversion of these purines to formamidopyrimidines. It was found that formamidopyrimidine-DNA glycosylase, known to remove imidazole-ring-opened 7-methylguanine from DNA, did not excise the radiation-induced non-alkylated form...

Journal: :Chemical & pharmaceutical bulletin 2002
Axel Reinhard Stoit Jos Hubertus Maria Lange Arnold Peter den Hartog Eric Ronken Koos Tipker Herman Heinrich van Stuivenberg Jessica Adriana Rigtje Dijksman Henri Cornelis Wals Chris Gerrit Kruse

The design, synthesis and biological activities of potent pyrazole-based tricyclic CB1 receptor antagonists (2) are described. The key synthetic step involves the ring closure of the lithiated alpha, gamma-keto ester adduct (4). The optimal nitroderivative (28) in this series exhibits a high CB1 receptor affinity (pKi=7.2) as well as very potent antagonistic activity (pA2=8.8) in vitro. The reg...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید