Although the majority of circulating ghrelin originates from the stomach, no prospective study of the proportion of ghrelin derived from the stomach has been reported. Patients with early gastric cancer who underwent gastric resection were divided into three groups according to the extent and site of gastric resection: subtotal gastrectomy group (n = 24), proximal gastrectomy group (n = 4), and...

background: prevalence of obesity in the world, in both developed and developing countries, is growing rapidly. bariatric surgery is now accepted as the treatment for morbid obesity. objective: this study compares laparoscopic sleeve gastrectomy's effectiveness (lsg) with the most common bariatric surgery, laparoscopic roux-en-y (lrygb) gastric bypass.   methods: a systematic review was perform...

BACKGROUND AND AIMS The gastric hormone ghrelin has been reported to stimulate food intake, increase weight gain, and cause obesity but its precise physiological role remains unclear. We investigated the long term effects of gastrectomy evoked ghrelin deficiency and of daily ghrelin injections on daily food intake, body weight, fat mass, lean body mass, and bone mass in mice. METHODS Ghrelin ...

BACKGROUND The relation between hunger, satiation, and integrated gastrointestinal motility and hormonal responses in morbidly obese patients after sleeve gastrectomy has not been determined. OBJECTIVE The objective was to assess the effects of sleeve gastrectomy on hunger, satiation, gastric and gallbladder motility, and gastrointestinal hormone response after a liquid meal test. DESIGN Th...

Introduction: Several therapeutic methods with different efficacy for dealing with obesity are presented. Different methods for treating obesity have been more successful in the treatment of gastrectomy. Despite the positive effect of this surgery in treating obesity, sleeve gastrectomy causes imbalance of hemodynamic parameters similar to other invasive interventions. Therefore, the aim of thi...

PURPOSE This study reports the impact of conversion from laparoscopic gastrectomy to open gastrectomy on the short- and long-term outcomes of patients with gastric cancer. METHODS Retrospective analysis of clinical and follow-up data of 236 patients with gastric cancer who underwent laparoscopic gastrectomy between January 2010 and October 2016 was performed. Patients were divided into the co...

Purpose Duodenal stump fistula (DSF) is a serious complication after gastrectomy for gastric cancer. Although risk evaluation and management of DSF were presented by some investigators, there was no technical attempt has been made to prevent DSF during laparoscopic gastrectomy until now. Methods Consecutive 99 patients were enrolled from April 2014 to February 2016 in 2 institutes. All patien...

BACKGROUND Laparoscope-assisted gastrectomy in treating patients with gastric cancers developed with a background of highly invasive traditional surgery and is being increasingly performed in the Asian Pacific area. This study systemically investigated the technique and clinical results for comparison with traditional radical subtotal gastrectomy for gastric cancers. METHODS Clinical studies ...

East Asian surgeons generally report lower morbidity and mortality rates for gastrectomy with D2 lymphadenectomy than do surgeons in Western countries; however, the disparity remains unexplained. The aim of this article was to determine the feasibility and safety regarding cases in which East Asian surgeons perform such procedures in Caucasian patients (CPs). Twelve CPs underwent gastrectomy wi...