Guinea pig hindlimbs were unilaterally immobilized at resting length to evaluate histochemical, biochemical, and contractile properties of immobilized muscle. Contralateral limbs remained unrestrained. Four weeks later contractile properties were measured under chloral hydrate anesthesia. Average time-to-peak tension of the immobilized soleus was 30% less, whereas that of the gastrocnemius was ...

BACKGROUND The trapezius muscle flap is not usually the first reconstructive option for skin and soft tissue defects in the posterior neck and scalp due to surgeons' unfamiliarity with the surgical anatomy and developments in free tissue transfer techniques. The goals of this study were to describe the clinical use of trapezius flaps in posterior neck and scalp reconstruction, and to investigat...

The superficial muscle group of the posterior compartment of leg forms a powerful muscular mass in the calf. The two-headed gastrocnemius is the most superficial muscle of this group, and forms the proximal, most prominent part of the calf. Gastrocnemius muscle exhibits numerous variations in the origin and/or insertion. The present report describes the incidental occurrence of the third/access...

Anserine and carnosine in the muscle of growing rats were measured to explore the effect of dietary methionine. Carnosine was reduced in the gastrocnemius muscle of rats fed on a methionine-free diet. After refeeding on methionine for one week, carnosine in the muscle approached to the normal level. In contrast, anserine increased in the muscle of rats fed on a methionine-free diet. Anserine al...

White JP, Baltgalvis KA, Puppa MJ, Sato S, Baynes JW, Carson JA. Muscle oxidative capacity during IL-6-dependent cancer cachexia. Am J Physiol Regul Integr Comp Physiol 300: R201–R211, 2011. First published December 9, 2010; doi:10.1152/ajpregu.00300.2010.—Many diseases are associated with catabolic conditions that induce skeletal muscle wasting. These various catabolic states may have similar ...

Many diseases are associated with catabolic conditions that induce skeletal muscle wasting. These various catabolic states may have similar and distinct mechanisms for inducing muscle protein loss. Mechanisms related to muscle wasting may also be related to muscle metabolism since glycolytic muscle fibers have greater wasting susceptibility with several diseases. The purpose of this study was t...

Denervation results in the accumulation of total lipids (94.68%), phospholipids (190.94%), cholesterol (31.82%) and triglycerides (30.86%) within 30 days in gastrocnemius muscle of adult mice. The treatment of denervated mice with beta-agonist isoproterenol (60 mg kg(-1) day(-1) for 30 days, orally) does not inhibit the increased lipid biosynthesis induced by the loss of neural supply to gastro...

Forehead-taps elicited short-latency motor responses in the lower leg muscle which, together with vestibulocollic reflexes, might contribute to multisensory control of posture. We tested this paradigm in human subjects standing upright in order to determine if the responses differed depending on whether the taps were to the forehead or temporal bone. Forehead-taps elicited short-latency inhibit...

BACKGROUND Extended Soft tissue defect of leg including middle and distal parts always has been a challenge for many plastic surgeons and also a frustrated problem for patients and families. To introduce the use of the soleus muscle and reverse sural flaps as synchronous surgical treatment alternative of the leg bone exposure with large soft tissue defect, this study was conducted. METHODS T...

AIM Calf muscle growth in children with unilateral cerebral palsy (UCP) and bilateral cerebral palsy (BCP) is unknown. This cross-sectional study examines the medial gastrocnemius growth rates of ambulatory children with UCP and BCP compared with children with typical development (CTD), aged 2 to 9 years. METHOD Fifty children with UCP (mean age 66mo [SD 18], 29 males, Gross Motor Function Cl...