Scleroderma is a complex multisystem connective tissue disorder. Early visceral disease, such as gastrointestinal (GI) involvement, associated with significant morbidity and poorer prognosis. Prompt diagnosis crucial to allow disease modifying therapies be initiated early in the course of disease. The primary underlying pathophysiology GI tract dysmotility, muscular atrophy, fibrosis, this refl...

OBJECTIVE To analyze the development and prevalence of gastrointestinal signs and symptoms associated with the development of the digestive tract, and to assess the measures aimed to reduce their negative impacts. SOURCE OF DATA Considering the scope and comprehensiveness of the subject, a systematic review of the literature was not carried out. The Medline database was used to identify refer...