BACKGROUND Microscopic colitis (MC) is a disease manifested by diarrhoea and is divided into collagenous and lymphocytic colitis. The aetiology is unknown, but auto-immunity is suggested. Auto-antibodies have been only rarely examined in this entity. The aim of the study was to examine the prevalence of auto-antibodies, and to examine associations between the presence of antibodies and clinical...

Experience suggests that many celiac patients suffer from persistent symptoms despite a long-term gluten-free diet (GFD). We investigated the prevalence and severity of these symptoms in patients with variable duration of GFD. Altogether, 856 patients were classified into untreated (n = 128), short-term GFD (1-2 years, n = 93) and long-term GFD (≥3 years, n = 635) groups. Analyses were made of ...

BACKGROUND & OBJECTIVES The immunosuppressants administered to renal transplant subjects are usually monitored therapeutically to prevent graft rejection and drug toxicity. Mycophenolic acid (MPA) is an immunosuppressant. The present prospective study was undertaken to establish the utility of plasma level monitoring of MPA and to correlate it with clinical outcomes in renal transplant receipie...

Background The vagus nerve emerges from the jugular foramen and continues through carotid sheath in cervical region. is contact with SCM muscle. It has been hypothesized that Sternokleidomastoideus (SCM) muscle tension may affect function of passing it. known there an increase activation individuals chronic neck pain (CNP), which change passive mechanical properties [1]. shown dysfunction can c...

Purpose: This study aimed to examine the association between preoperative anxiety and gastrointestinal symptoms. Materials Methods: The sample of this descriptive, comparative research comprised 270 patients in a state hospital located northeast Turkey. First, Trait Anxiety Scale Gastrointestinal Symptom Rating Scale-1 were used collect data from at time admission. Then, State Scale-2 completed...

Abstract Background Most cardiac surgeries are associated with post-sternotomy pain syndrome. Pain causes elevation of blood pressure, heart rate and may be hemodynamic instability, respiratory infections, other postoperative complications. Non-steroidal anti-inflammatory drugs (NSAIDs) among the most commonly used analgesics in surgery. The majority NSAIDs metabolized by cytochrome P-450. mech...

BACKGROUND Internet-based cognitive behavior therapy (ICBT) has shown promising effects in the treatment of irritable bowel syndrome (IBS). However, to date no study has used a design where participants have been sampled solely from a clinical population. We aimed to investigate the acceptability, effectiveness, and cost-effectiveness of ICBT for IBS using a consecutively recruited sample from ...

Upper and lower gastrointestinal dysautonomia symptoms (GIDS)--sialorrhea, dysphagia, and constipation are common in Parkinson's disease (PD) and often socially as well as physically disabling for patients. Available invasive quantitative measures for assessing these symptoms and their response to therapy are time-consuming, require specialized equipment, can cause patient discomfort and presen...

BACKGROUND Continuous feedback on patient improvement and the therapeutic alliance may reduce the number of dropouts and increase patient outcome. There are, however, only three published randomized trials on the effect of feedback on the treatment of eating disorders, showing inconclusive results, and there are no randomized trials on the effect of feedback in group therapy. Accordingly the cu...

CONTEXT Patients with Addison's disease (AD) report impaired subjective health status (SHS). Since cortisol exhibits a robust circadian cycle that entrains other biological clocks, impaired SHS may be due to the noncircadian cortisol profile achieved with conventional glucocorticoid replacement. Continuous subcutaneous hydrocortisone infusion (CSHI) reproduces a circadian cortisol profile, but ...