This research studied the viability of probiotic bacterium Lactobacillus plantarum (L. plantarum) encapsulated in internal aqueous phase (W1) a water-in-oil-in-water (W1/O/W2) emulsion system, with help gelation and different gelling agents. Additionally, physicochemical, rheological, microstructural properties fabricated systems were assessed over time under effect W1 gelation. The average dro...

Pathogenesis in sickle cell disease depends on whether red blood cells can pass the microvasculature during the delay time before hemoglobin S gelation and cell rigidification occur. Here we observe individual hemoglobin S fibers by differential interference contrast (DIC) microscopy and show that hemoglobin S gels and fibers are fragile and easily broken by mechanical perturbation, and that br...

Purpose: To develop ampicillin trihydrate-loaded chitosan nanoparticles by modified ionic gelation method and evaluate their antimicrobial activity. Methods: Ampicillin trihydrate-loaded chitosan nanoparticles were prepared by ionic gelation method with the aid of sonication. Parameters such as the zeta potential, polydispersity, particle size, entrapment efficiency and in vitro drug release of...

oft materials, such as gels and colloidal glasses, often exhibit different rheological properties at ulk and microscopic scales as a result of their complex microstructure. This phenomenon has ecently been demonstrated for a gel-forming aqueous dispersion of Laponite clay Oppong et al. hys. Rev. E 78, 021405 2008 . For this material, microrheology reveals a significantly weaker el and a longer ...

The kinetics of hemoglobin S gelation are critical in sickle disease because microvascular obstruction can be avoided if red blood cells pass these vessels during the delay time, before polymerization and gelation occur in sufficient degree to rigidify the cells. Kinetics, including the delay time and the closely related exponential progress rate, are highly sensitive to hemoglobin concentratio...

Particle-tracking methods are used to study gelation in a colloidal suspension of Laponite clay particles. We track the motion of small fluorescent polystyrene spheres added to the suspension, and obtain the micron-scale viscous and elastic moduli of the material from their mean-squared displacement. The fluorescent spheres move subdiffusively due to the microstructure of the suspension, with t...

The goal of this study was to develop floating microspheres that could be used as gastroretentive systems for the delivery of anthocyanins (ACNs). These compounds are absorbed in the stomach and small intestine, and insufficient residence time in these organs could result in limited absorption and contribute to degradation. The microparticles containing freeze-dried haskap berry extract (321.96...

The contracted pellets derived from a high-speed supernate of Dictyostelium discoideum (S3) were investigated to determine the functional activity associated with this specific subset of the cellular motile apparatus. A partially purified model system of gelation and contraction (S6) was prepared from the contracted pellets, and the presence of calcium- and pH-sensitive gelation and contraction...

Phase transitions of linear multivalent proteins control the reversible formation of many intracellular membraneless bodies. Specific non-covalent crosslinks involving domains/motifs lead to system-spanning networks referred to as gels. Gelation transitions can occur with or without phase separation. In gelation driven by phase separation multivalent proteins and their ligands condense into den...