In this study the in vitro activities and pharmacodynamic properties of moxifloxacin, levofloxacin, gatifloxacin and gemifloxacin were compared on recently isolated respiratory pathogens and strains of Streptococcus pneumoniae with known mechanisms of fluoroquinolone resistance. In addition, the resistance selection frequencies of moxifloxacin and levofloxacin on three recently isolated respira...

SIMPLE, RAPID, AND EXTRACTIVE SPECTROPHOTOMETRIC METHODS WERE DEVELOPED FOR THE DETERMINATION OF SOME FLUOROQUINOLONES ANTIBIOTICS: gemifloxacin mesylate (GMF), moxifloxacin hydrochloride (MXF), and enrofloxacin (ENF) in pure forms and pharmaceutical formulations. These methods are based on the formation of ion-pair complexes between the basic drugs and acid dyes, namely, bromocresol green (BCG...

Aim of present work was to develop and validate a simple, precise accurate uv-vis spectrophotometric method for the simultaneous estimation gemifloxacin mesylate (GEMI) ambroxol HCl (AMB) in their combined tablet dosage form. The is based on first-order derivative spectroscopy. For determination sampling wavelengths, each GEMI AMB were scanned wavelength range 200–400 nm spectrum mode wavelengt...