نتایج جستجو برای: gene regulatory networks
تعداد نتایج: 1656653 فیلتر نتایج به سال:
Introduction: The major issue for the future of bioinformatics is the design of tools to determine the functions and all products of single-cell genes. This requires the integration of different biological disciplines as well as sophisticated mathematical and statistical tools. This study revealed that data mining techniques can be used to develop models for diagnosing high-risk or low-risk lif...
Organismal development and many cell biological processes are organized in a modular fashion, where regulatory molecules form groups with many interactions within a group and few interactions between groups. Thus, the activity of elements within a module depends little on elements outside of it. Modularity facilitates the production of heritable variation and of evolutionary innovations. There ...
Цель работы состоит в развитии подхода к моделированию генных регуляторных сетей с учетом модульной структуры гена. Модель строится на основе экспериментальных данных и последующей экспериментальной верификации. Особенность подхода состоит в том, в модель включают дополнительные молекулярно-биологические детали, что более реалистично отражает механизмы контроля генной активности. Модельным объе...
ATTED-II (http://atted.jp) is a database of gene coexpression in Arabidopsis that can be used to design a wide variety of experiments, including the prioritization of genes for functional identification or for studies of regulatory relationships. Here, we report updates of ATTED-II that focus especially on functionalities for constructing gene networks with regard to the following points: (i) i...
This paper proposes a new method to evaluate the complexity of a Gene Regulatory Network (GRN). It is based on the generation of pictures. In addition to being visually interesting, the pictures shows the capacity of the GRN to produce smooth and/or sudden transitions, fractal-like complexity and regularities. We also have studied the influence of the size of the GRN on the complexity of pictur...
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