the overwhelming rate of progress in biotechnological research especially in human genetics, as well as the high levels of power these researches provide us to intervene in human lives, brings serious concerns on the ethical problems that may rise from these research endeavors. to address this critical issue in iran, we conducted a study issuing publishing authors of studies in human genetics f...

angiotensin converting enzyme (ace; omim: 106180) has an important role in the conversion of angiotensin i to angiotensin ii and degradation of bradykinin. genetic polymorphism i/d (rs4646994) in the gene encoding ace has been well defined. to get more insight into the genetic structure of iranian populations, the distribution of the ace i/d polymorphism among iranians was compared with each ot...

this paper presents a model for constrained multiobjective optimization of mixed-cropping planning. the decision challenges that are normally faced by farmers include what to plant, when to plant, where to plant and how much to plant in order to yield maximum output. consequently, the central objective of this work is to concurrently maximize net profit, maximize crop production and minimize pl...

Abstract— A real coded genetic algorithm is applied for designing infinite impulse response (IIR) filter based on L1approximation error criterion. The proposed real coded genetic algorithm, which is a technique for optimization inspired by genetics and natural evolution method, enhances the search capability and provides a fast convergence for calculating the optimal filter coefficients. The fi...

We propose a new algorithm to do posterior sampling of Kingman’s coalescent, based upon the Particle Markov Chain Monte Carlo methodology. Specifically, the algorithm is an instantiation of the Particle Gibbs Sampling method, which alternately samples coalescent times conditioned on coalescent tree structures, and tree structures conditioned on coalescent times via the conditional Sequential Mo...

This paper proposes an optimisation algorithm for designing an optimal implementation path for a charging cordon scheme. The main incentive for time-dependent design is public acceptability issue. A simple equilibrium based time-dependent model is defined. Different patterns of the implementation path are investigated including (i) evolution of a single cordon, (ii) single cordon and additional...

The detection of change-points in a spatially or time ordered data sequence is an important problem in many fields such as genetics and finance. We derive the asymptotic distribution of a statistic recently suggested for detecting change-points. Simulation of its estimated limit distribution leads to a new and computationally efficient change-point detection algorithm, which can be used on very...

background: the goal of the present study was to report the results of two parallel works in which the incidence of fetal deaths and also congenital malformations among the progenies of the iranian chemical victims were studied. methods: the subjects were progenies of a randomly selected population from survivors of chemical attacks during iran-iraq conflict. totally 807 male cases ranged 18-85...

actins are small globular filaments functioning in cell processes like muscle contraction, and stabilized to the sarcomeric z- discs by actin binding proteins (actinins). one of the important gene coding for actin binding proteins in fast twitch fibers is alpha- actinin- 3 (actn3). in this research, we have conducted a gene profile study investigating the genotype and allele distributions of ac...