background: tumor necrosis factor-beta or lymphotoxin-alpha (lt- α ), il-4 and il-10 are determining factors in immunity against bcg.  allelic polymorphisms in the regulatory regions of their genes affect the rate of cytokine production and therefore, the host’s ability in bcg containment.   objective : to study the prevalence of –590 (c/t) and –592 (c/a) allelic distribution of il-4 and il-10 ...

Background: The tumor suppressor gene TP53 (alias p53) located on chromosome 17 is involved in various cancers. Case-control studies have shown that p53 codon 72 polymorphism modulates the prognosis and susceptibility to various malignancies. We undertook the present study to explore a possible association between mucinous and non-mucinous adenocarcinomas with different genotypes or alleles at ...