نتایج جستجو برای: genotyped individuals
تعداد نتایج: 340120 فیلتر نتایج به سال:
INTRODUCTION In sub-Saharan Africa, approximately 100 million people have CKD, yet genetic risk factors are not well-understood. Despite the potential importance of understanding APOL1 risk allele status among individuals with CKD, little genetic research has been conducted. Therefore, we conducted a pilot study evaluating the feasibility of and willingness to participate in genetic research on...
background: cytochrome p450 2c19 (cyp2c19) is important in metabolism of wide range of drugs. cyp2c19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (urm). distribution of this variant allele has not been well studied worldwide. the aim of present study was to investigate allele and genotype frequencies of cyp2c19*17 in...
Background and aims – Chilgoza pine ( Pinus gerardiana) is a near-threatened tree species from the north-western Himalayas. This economically most important in Afghanistan because of its edible nuts; however, distribution range disjunct restricted to few isolated regions. The IUCN lists as near threatened overexploitation nuts declining population trend. research first in-depth analysis genetic...
aim : this study investigated the role of cd86 +237 g/c polymorphism in intensifying the risk of crc development. background : colorectal cancer (crc) is a multi-factorial diseases. genetic background could affect the susceptibility of individuals to crc development. cd86 is a co-stimulatory factor on antigen-presenting cells that plays key roles in several cancer related mechanisms such as aut...
a total of 125 russian red pied cows were genotyped for the prolactim-related gene. the prl-rsai genotypes were analysed using the polymerase chain reaction -restriction fragment length polymorphism (pcr-rflp) method. in this breed, the frequencies of alleles were as follows; a= 0.794 and b= 0.206. the frequencies of aa, ab and bb genotypes were 0.598, 0.392 and 0.01; respectively. results sho...
BACKGROUND AND PURPOSE Extracellular adenosine triphosphate (ATP) regulates inflammatory cells by activation of the P2X(7) receptor. We hypothesized that polymorphisms in P2RX7 influence the risk of ischemic heart disease (IHD), ischemic stroke (IS) and cardiovascular risk factors and tested this hypothesis using genetic association studies. METHODS Two loss-of-function SNPs in P2RX7 were gen...
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