نتایج جستجو برای: geum

تعداد نتایج: 245  

Journal: :International Journal of Systematic and Evolutionary Microbiology 2014

Journal: :Current Biology 2008
Jessie Yanxiang Guo Ayumi Yamada Taisuke Kajino Judy Qiju Wu Wanli Tang Christopher D. Freel Junjie Feng B. Nelson Chau Michael Zhuo Wang Seth S. Margolis Hae Yong Yoo Xiao-Fan Wang William G. Dunphy Pablo M. Irusta J. Marie Hardwick Sally Kornbluth

BACKGROUND In response to DNA damage, cells undergo either cell-cycle arrest or apoptosis, depending on the extent of damage and the cell's capacity for DNA repair. Cell-cycle arrest induced by double-stranded DNA breaks depends on activation of the ataxia-telangiectasia (ATM) protein kinase, which phosphorylates cell-cycle effectors such as Chk2 and p53 to inhibit cell-cycle progression. ATM i...

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