We describe recent discoveries of low column density (NHI ≤ 10 cm) H I Lyα absorbers made with the Hubble Space Telescope (HST) which have allowed us a first look at gas in local intergalactic space between us and the “Great Wall”. Despite the mere 2.4m aperture of HST, these new observations allow us to detect absorbers with column densities, NHI ≈ 10 12.5 cm, as low as those found using Keck/...

We have analyzed the GH receptor (GHR) gene in four individuals with Laron syndrome, and a missense mutation was identified for each patient in the extracellular domain of the GHR (D152H, I153T, Q154P, and V155G). The D152H mutation was previously reported. We have reproduced the three novel mutations in the GHR complementary DNA and analyzed their consequences in human 293 transfected cells. I...

Somatostatins (SSs), a diverse family of peptide hormones, have been shown to inhibit the release of growth hormone (GH) from the pituitary. In this study, we used rainbow trout to determine whether or not SSs affect growth in an extrapituitary manner, in particular, by decreasing GH sensitivity in liver. SS-14 significantly decreased hepatic GH binding in fish implanted (5.8 x 10(-11) mol/h) f...

Data in the λ2090 B region of HD 76932 have been obtained at high S/N using the HST GHRS echelle at a resolution of 90,000. This wavelength region has been previously identified as a likely candidate for observing the B/B isotopic splitting. The observations do not match a calculated line profile extremely well at any abundance for any isotopic ratio. If the B abundance previously determined fr...

During a period of 18 months 5 Hubble–Space– Telescope GHRS interplanetary HLyα glow spectra were obtained at different lines of sight from different positions of the earth on its orbit, but despite employment of a radiation transport model that takes into account the angle–dependent partial frequency redistribution, the self-absorption by interplanetary hydrogen, the realistic spectral profile...

We have obtained spectra of three QSO/AGNs with the GHRS aboard the Hubble Space Telescope to search for absorption from low column density gas in the halo of the dwarf spheroidal (dSph) galaxy Leo I. The probe sight lines pass 2.1, 3.7, and 8.1 kpc from the center of the galaxy, but no C IV, Si II, or Si IV absorption is found at the velocity of Leo I. The absence of low-ionization species sug...

In a ongoing programme aimed at studying galaxy counterparts of Damped Lyα Absorbers (DLAs) we have obtained high resolution deep I-band imaging data of the field around the z em = 0.457 BAL QSO Q2112+059. In the literature this QSO is listed to have a candidate DLA at z abs = 0.2039 along the line of sight. After subtraction of the QSO Point Spread Function (PSF) we detect a galaxy centred on ...

We use new Space Telescope Imaging Spectrograph (STIS) and archival Goddard High Resolution Spectrograph (GHRS) observations to study interstellar B II j1362 and O I j1355 absorption along seven sight lines. Our new column density measurements, combined with measurements of four sight lines from the literature, allow us to study the relative B/O abundances over a wide range of interstellar envi...

We present an analysis of high resolution HST Space Telescope Imaging Spectrograph (STIS) observations of O I λ1356 and H I Lyman-α absorption in 36 sight lines that probe a variety of Galactic disk environments and include paths that range over nearly 4 orders of magnitude in f(H2), over 2 orders of magnitude in 〈nH〉, and that extend up to 6.5 kpc in length. Since the majority of these sight l...

Two UV brights stars in globular clusters, ROA 5701 (ω Cen) and Barnard 29 (M 13) are analysed from high-resolution UV and optical spectra. The main aim is the measurement of iron abundances from UV spectra obtained with the HST-GHRS. In addition atmospheric parameters and abundances for He, C, N, O, and Si are derived from optical spectra (ESO CASPEC) for ROA 5701 or taken from literature for ...