OBJECTIVE In this study the effectiveness of prolotherapy in the treatment of deficient load transfer of the sacroiliac joint (SIJ) was determined. DESIGN A prospective descriptive study. SETTING Authors' private practice. PARTICIPANTS 25 patients who consented to treatment and attended for at least one follow-up visit and assessment. STUDY PERIOD From April 2004 to July 2007. INTERVE...

Malignant gliomas are the most frequent primary brain tumors in adults. Temozolomide is an oral alkylating cytotoxic agent of second generation, used in the treatment of high-grade gliomas. It is indicated in newly diagnosed glioblastoma multiform as well as in recurrent or progressive malignant gliomas, such as glioblastoma multiform or anaplastic astrocytoma. However, temozolomide is also use...

Glioblastoma multiform is a primary brain tumor derived from glial cells. The aim of this study to investigate how glutamate metabolism regulated by transporter 1 (GLT-1) degradation pathway in glioblastoma and cell lines. protein expression levels GLT-1, total ubiquitin, kinase C (PKC) proteins involved the GLT-1 were measured western blot technique. Additionally, cells, level accumulated medi...

Many studies have focused on the prognosis role of insulin-like growth factor binding protein 2 (IGFBP2) in glioma patients, but the results remain inconsistent. Thus, a meta-analysis was carried out to explore the relationship between IGFBP2 and glioma prognosis. Relevant publications were searched in several widely used databases and six articles (seven studies, 766 patients in all) were incl...

This article investigates the multiform, multiscreen interactive film installation, Crossed Lines (20022007, Dir: Sarah Atkinson). Crossed Lines amalgamates multiform plots, multiscreen viewing environments, interactive interfaces and interactive story navigation forms into one storytelling paradigm. My research probes the challenges of designing, authoring and scripting such an ambitious piece...