نتایج جستجو برای: glioblastoma multiform radiomics

تعداد نتایج: 27305  

Journal: :iranian journal of nuclear medicine 1996
regina roman steven j brown curtis miyamoto lalitha krishna walter slizofski

thallium 201 whole body scintigraphy was performed in a 30 year old patient with diffuse osseous metastatic disease secondary to glioblastoma multiforme. multiple sites of thallium uptake correlated with the findings on serial bone scans and radiographs. bone biopsy of a lower lumbar vertebra confirmed that the metastases were of glial origin.

2017
Kaixian Yu Youyi Zhang Yang Yu Chao Huang Rongjie Liu Tengfei Li Liuqing Yang Jeffrey S. Morris Veerabhadran Baladandayuthapani Hongtu Zhu

Human Papilloma Virus (HPV) has been associated with oropharyngeal cancer prognosis. Traditionally the HPV status is tested through invasive lab test. Recently, the rapid development of statistical image analysis techniques has enabled precise quantitative analysis of medical images. The quantitative analysis of Computed Tomography (CT) provides a non-invasive way to assess HPV status for oroph...

2016
Panpan Hu Jiazhou Wang Haoyu Zhong Zhen Zhou Lijun Shen Weigang Hu Zhen Zhang

PURPOSE To evaluate the reproducibility of radiomics features by repeating computed tomographic (CT) scans in rectal cancer. To choose stable radiomics features for rectal cancer. RESULTS Volume normalized features are much more reproducible than unnormalized features. The average value of all slices is the most reproducible feature type in rectal cancer. Different filters have little effect ...

2014
Jun Cai Yanting Zhang Xiaoxin Bai Shaoxue Li Jinhua Chen Ruicong Chen Hao Lin Shengping Huang

BACKGROUND Cases with brain tumor and subdural hematoma are rare; surgical management of the elderly patients with a glioblastoma multiform (GBM) and a chronic subdural hematoma (CSDH) can be intractable. CASE DESCRIPTION We report a 77-year-old patient, who had a left front lobe GBM and a giant, calcified, left frontoparietaloccipitotemporal CSDH. The patient recovered well from anesthesia a...

2018
Stéphanie Lhomond Tony Avril Nicolas Dejeans Konstantinos Voutetakis Dimitrios Doultsinos Mari McMahon Raphaël Pineau Joanna Obacz Olga Papadodima Florence Jouan Heloise Bourien Marianthi Logotheti Gwénaële Jégou Néstor Pallares-Lupon Kathleen Schmit Pierre-Jean Le Reste Amandine Etcheverry Jean Mosser Kim Barroso Elodie Vauléon Marion Maurel Afshin Samali John B Patterson Olivier Pluquet Claudio Hetz Véronique Quillien Aristotelis Chatziioannou Eric Chevet

Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical role in cancer development. This concept is valid in glioblastoma multiform (GBM), the most lethal primary brain cancer with no effective treatment. We previously demonstrated...

2017
Faiq A. Shaikh Omer Awan

Radiomics can be defined as the extraction and analysis of large amounts of advanced quantitative imaging features with high throughput from medical images obtained with various modalities [1]. Radiomics methods can be applied across various cancers to identify tumor phenotype characteristics in the images that correlate with their likelihood of survival, as well as their association with the u...

2016
Rakesh Shiradkar Tarun K Podder Ahmad Algohary Satish Viswanath Rodney J Ellis Anant Madabhushi

BACKGROUND Radiomics or computer - extracted texture features have been shown to achieve superior performance than multiparametric MRI (mpMRI) signal intensities alone in targeting prostate cancer (PCa) lesions. Radiomics along with deformable co-registration tools can be used to develop a framework to generate targeted focal radiotherapy treatment plans. METHODS The Rad-TRaP framework compri...

Journal: :basic and clinical cancer research 0
ali-reza khoshnevisan iranian center of neurological research, tehran university of medical sciences ahad muhammadnejad cancer research center, tehran university of medical sciences samad muhammadnejad cancer research center, tehran university of medical sciences zohreh mazaheri cancer research center, tehran university of medical sciences maryam kazem haghighi cancer research center, tehran university of medical sciences farrokh tirgari cancer research center, tehran university of medical sciences

background: gbm is the most common and malignant astrocity tumor and it is persistent to common treatment so, these patients have a very low survival. several researchers around the world, including iran, have been investigated gbm-cell line in vitro. however in vivo studies have not been fulfilled. methods : as standard cell line (u-87mg) derived from human gbm and total gbm tumor derived from...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2009
M Schaich L Kestel M Pfirrmann K Robel T Illmer M Kramer C Dill G Ehninger G Schackert D Krex

BACKGROUND Some patients with glioblastoma multiform do not respond to temozolomide even though they have aberrant promoter methylation of the DNA repair enzyme O(6)-methylguanine methyltransferase (MGMT). This suggests that additional factors hamper temozolomide cytotoxicity. We aimed to confirm first that temozolomide is a target for the multidrug resistance transporter MDR1/ABCB1 and second ...

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