This study examines the relationship between common genetic variation within DNA methyltransferase genes and inter-individual variation in DNA methylation. Eleven polymorphisms spanning DNMT1 and DNMT3B were genotyped. Global and gene specific (IGF2, IGFBP3, ZNT5) DNA methylation was quantified by LUMA and bisulfite Pyrosequencing assays, respectively, in neonatal cord blood and in maternal per...

Understanding how natural selection determines species’ life histories can reveal their resilience or sensitivity to anthropogenic changes. For example, the safe harbor hypothesis posits that will favor maximize time spent in safest stages; a second theoretical prediction suggests species with complex growth potential of stage relative its safety. Amphibians exhibit histories, diversity develop...

We investigate predictability in national equity market returns, and its relation to global economic risks. We show how to consistently estimate the fraction of the predictable variation that is captured by an assetpricing modelfor the expected returns. We use a model in which conditional betas of the national equity markets depend on local information variables, while global risk premia depend...

[1] Global land evapotranspiration (E) between 1982 and 2011 was estimated by using a canopy conductance-based process E model (Air Relative Humidity-Based Two-Source model) [Yan et al., 2012]. To analyze the impact of precipitation forcing on E, an ensemble of six E data sets was derived from a driving ensemble of six precipitation data sets (i.e., Global Historical Climatology Network, Global...