Acalypha indica (Indian Nettle in English, Kuppaimeni Tamil, Kuppameniya Sinhala) leaves are locally used as herbal remedy. It can induce hemolysis and methemoglobinemia a Glucose-6-Phosphate Dehydrogenase (G6PD) deficient person. Here we report 46-year-old-male was presented with following ingestion. Later, he found to have G6PD deficiency. He completely recovered supportive treatment.

A new variant of G6PD associated with chronic non-spherocytic haemolytic anaemia (CNSHA) in an Irish male is described. This variant is unique in that it has a normal electrophoretic mobility, Michaelis constant for G6P and NADP, and a normal pH optimum, together with a marked increase in utilisation of the substrate 2 deoxy glucose-6-phosphate. It is also relatively heat stable when compared w...

From 1981 to 1983, 15,097 X-chromosomes were genetically extracted from a number of North American populations of D. melanogaster and were electrophoretically screened for rare mobility and activity variants of glucose-6-phosphate dehydrogenase (G6PD). Overall, 13 rare variants were recovered for a frequency of about 10(-3). Eleven variants affect electrophoretic mobility and are apparently str...