Dopaminergic signaling is one of the regulatory pathways being investigated for its implication in glucose metabolism. The aim of this study was to determine the effect of cabergoline on biochemical and anthropometric parameters in prediabetes stage (impaired fasting glucose and impaired glucose tolerance). In this double blind, placebo-controlled, pilot study, 27 prediabetic adults were random...

Objective: This study aims to estimate and compare the time-course change in blood glucose levels by blood cells in serum, and plasma with or without preservatives, which may reflect the rate of glucose utilization by blood cells. Method: This laboratory-based cross-sectional study was carried out using a blood specimen of 28 participants among which 14 were diagnosed with diabetes and 14 were...

abstract        background and objective: the association of triglyceride/high density lipoprotein-cholesterol (tg/hdl-c) ratio with fasting serum insulin, which is an alternative method of insulin resistance (ir) measurement, is well-recognized. thus, the measurement of tg/hdl-c ratio is useful to determine both ir and dyslipidemia, which itself is a characteristic of individuals with ir. ther...

Recent studies show that adrenergic agonists and inflammatory cytokines can stimulate skeletal muscle glucose uptake, but it is unclear if glucose oxidation is similarly increased. Thus, the objective of this study was to determine the effects of ractopamine HCl (β1 agonist), zilpaterol HCl (β2 agonist), TNFα, and IL-6 on glucose uptake and oxidation rates in unstimulated and insulin-stimulated...

<p>The objective of the present study is to obtain quantity honey components such as moisture, glucose, fructose and sucrose in order access quality honey. The tested samples are authenticated if characteristics a pure average ratio 56% 44% but ratios individual honeys ranged from high 64% 36% glucose low 50% glucose. contents due presence invertase enzymes. organic acids responsible for ...

In vitro activation of adipose tissue glycogen synthetase caused a change in kinetic properties of the enzyme. The nonactivated enzyme had a K, for UDP-glucose of 2 m when measured without glucose-6-P. The K, decreased to 0.7 mM in the presence of 2 mM glucose-6-P. The K, for UDP-glucose of the activated enzyme was 0.8 mM. Glucose-6-P affected both the K, for UDP-glucose and the v m&x of the no...

The purpose of this study was to investigate how renal loss of both C-peptide and glucose during oral glucose tolerance test (OGTT) relate to and affect plasma-derived oral minimal model (OMM) indices. All individuals were recruited during family screening between August 2007 and January 2011 and underwent a 3.5-h OGTT, collecting nine plasma samples and urine during OGTT. We obtained the follo...

objectives: to investigate fasting glucose, glucose tolerance, insulin resistance and insulin–like growth factor 1 in patients with or without colorectal polyps. materials and methods: in this cross-sectional study, we evaluated fasting glucose, insulin, insulin–like growth factor 1 (igf-1), lipid profile and glucose tolerance test in 103 patients undergoing colonoscopy (52 normal and 53 with a...

1. Insulin resistance after surgery has been shown to be related to several important derangements in protein and fat metabolism. However, mechanisms of impaired glucose tolerance after surgery remain ill-defined. 2. Insulin sensitivity and glucose kinetics (6,6(2)H2-glucose) were studied in seven patients before and after elective surgery (surgery group), by two step-hyperinsulinaemic (0.3 and...

To assess possible cellular mechanisms of in vitro resistance in noninsulin-dependent diabetes mellitus (NIDDM), maximum insulin-stimulated glucose transport and utilization and insulin binding were measured in adipocytes isolated from weight-matched normal glycemic subjects and patients with NIDDM. Glucose transport rate was determined by measuring the amount of [U-14C]-D-glucose taken up by i...